Press Releases October 5, 2026 04:05 PM

Aligos Therapeutics Announces Five Abstracts Accepted for Presentation at The Liver Meeting® 2026

Aligos Therapeutics to Present Five Abstracts Highlighting Innovative Therapies for Chronic Hepatitis B at The Liver Meeting® 2026

By Caleb Monroe
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Aligos Therapeutics announced that five of its research abstracts have been accepted for presentation at the AASLD The Liver Meeting® 2026, highlighting the company's advances in novel therapies for chronic hepatitis B virus (HBV) infection and hepatitis delta virus. These presentations focus on their potentially best-in-class small molecule CAM-E pevifoscorvir sodium and antisense oligonucleotide ALG-170675, demonstrating promising preclinical and clinical data. This recognition underscores Aligos' commitment to developing innovative treatments for liver and viral diseases with high unmet medical needs.

Aligos Therapeutics Announces Five Abstracts Accepted for Presentation at The Liver Meeting® 2026
ALGS
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Key Points

  • Five Aligos Therapeutics abstracts accepted for presentation at AASLD's The Liver Meeting® 2026, evidencing active clinical and preclinical research progress.
  • Focus on pevifoscorvir sodium (small molecule CAM-E) showing immune-modulatory effects and superiority in HBV suppression over existing nucleos(t)ide analogs.
  • Presentation of promising data on antisense oligonucleotide ALG-170675 and antiviral effects against hepatitis delta virus, indicating pipeline diversity and potential therapeutic impact.
  • The news impacts the biotechnology and pharmaceutical sectors, particularly companies involved in liver disease and viral therapy development.

SOUTH SAN FRANCISCO, Calif., Oct. 05, 2026 (GLOBE NEWSWIRE) -- Aligos Therapeutics, Inc. (Nasdaq: ALGS), a clinical stage biopharmaceutical company focused on improving patient outcomes through best-in-class therapies for liver and viral diseases, today announced five abstracts have been accepted for presentation at the American Association for the Study of Liver Disease’s (AASLD) The Liver Meeting® 2026, being held November 5 – 9, 2026 in Denver, CO. The abstracts released today can be found on the AASLD website at https://www.aasld.org/the-liver-meeting.

Details on the abstracts are as follows:

Pevifoscorvir sodium: Potential first-/best-in-class small molecule CAM-E for chronic hepatitis B virus (HBV) infection

Abstract #: 4139
Title: Immune-modulatory effects of pevifoscorvir sodium in HBeAg-positive patients with chronic hepatitis B infection
Presenter: Professor Lung-Yi Loey Mak, MBBS(HK), MD(HK), MRCP(UK), PDipID (HK), FHKCP, FHKAM (Medicine), FRCP (Glasg), FRCP (Edin), FRCP, Clinical Assistant Professor at The University of Hong Kong
Date/Time: November 8, 2026 at 1:00pm – 2:00pm MT
Session: Hepatitis B ("4001-4193"); Poster of Distinction

Abstract #: 4142
Title: Pevifoscorvir Sodium Reduces HBsAg Levels to < 3000 IU/mL in HBeAg Positive Subjects with Chronic HBV Infection Following Long-Term On-Study Treatment
Presenter: Professor Man-Fung Yuen, MBBS, MD, PhD, DSc, Chair and Chief of the Division of Gastroenterology and Hepatology, University of Hong Kong
Date/Time: November 8, 2026 at 1:00pm – 2:00pm MT
Session: Hepatitis B ("4001-4193")

Abstract #: 4158
Title: Pevifoscorvir Sodium (CAM-E) is Superior to Nucleos(t)ide Analogs in Suppressing Hepatitis B Virus Double-stranded Linear DNA In Vitro
Presenter: Andreas Jekle, PhD
Date/Time: November 8, 2026 at 1:00pm – 2:00pm MT
Session: Hepatitis B ("4001-4193")

ALG-170675: Potential best-in-class antisense oligonucleotide (ASO) for chronic hepatitis B virus (HBV) infection

Abstract #: 4156
Title: The potentially best-in-class HBV ASO ALG-170675 demonstrates a favourable preclinical profile: efficacy in an AAV-HBV mouse model, pharmacokinetics and safety in mouse and monkey
Presenter: Jin Hong, PhD
Date/Time: November 8, 2026 at 1:00pm – 2:00pm MT
Session: Hepatitis B ("4001-4193")

Preclinical

Abstract #: 3224
Title: Potent Inhibition of Hepatitis Delta Virus Replication by the Antisense Oligonucleotide ALG-215007
Presenter: Kellan Passow, PhD
Date/Time: November 7, 2026 at 1:00pm – 2:00pm MT
Session: Hepatitis - Other Infections ("3195-3246")

About Aligos

Aligos Therapeutics, Inc. (NASDAQ: ALGS) is a clinical stage biotechnology company founded with the mission to improve patient outcomes by developing best-in-class therapies for the treatment of liver and viral diseases. Aligos applies its science driven approach and deep R&D expertise to advance its purpose-built pipeline of therapeutics for high unmet medical needs such as chronic hepatitis B virus infection.

For more information, please visit www.aligos.com or follow us on LinkedIn or X.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the U.S. Private Securities Litigation Reform Act of 1995. Any statements in this press release that are not historical facts may be considered “forward-looking statements,” including without limitation, statements regarding Aligos’ plans to advance its pipeline and develop best-in-class therapies for the treatment of liver and viral diseases. Such forward looking statements are subject to substantial risks and uncertainties that could cause our development programs, future results, performance, or achievements to differ materially from those anticipated in the forward-looking statements. Such risks and uncertainties include, without limitation, risks and uncertainties inherent in the drug development process, including Aligos’ clinical-stage of development, the process of designing and conducting clinical trials, the regulatory approval processes, and other matters that could affect the sufficiency of Aligos’ capital resources to fund operations. For a further description of the risks and uncertainties that could cause actual results to differ from those anticipated in these forward-looking statements, as well as risks relating to the business of Aligos in general, see Aligos’ Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 6, 2026 and its future periodic reports to be filed or submitted with the Securities and Exchange Commission. Except as required by law, Aligos undertakes no obligation to update any forward-looking statements to reflect new information, events or circumstances, or to reflect the occurrence of unanticipated events.

Investor Contact
Aligos Therapeutics, Inc.
Jordyn Tarazi
Vice President, Investor Relations & Corporate Communications
+1 (650) 910-0427
[email protected]


Risks

  • Clinical-stage development carries inherent risks including negative or inconclusive trial outcomes for pevifoscorvir sodium and ALG-170675, which can impact approval timelines and commercial viability.
  • Regulatory approval is uncertain and dependent on successful clinical results and compliance with FDA and other authorities’ requirements.
  • Financial risks related to capital sufficiency to fund ongoing operations and R&D activities, as mentioned in the forward-looking statements and SEC filings.

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