Insider Trading June 3, 2026 05:07 PM

Vaxcyte COO Jim Wassil Executes Stock Sale Under 10b5-1 Plan Amid Vaccine Development Milestones

Analysis of insider activity and recent clinical trial progress for PCVX, examining valuation metrics and key development candidates.

By Derek Hwang PCVX

Jim Wassil, Chief Operating Officer at Vaxcyte, Inc., recently sold a total value of $111,415 worth of common stock. These transactions were executed on June 1, 2026, utilizing a pre-arranged Rule 10b5-1 trading plan adopted previously. Despite the sale, the company continues to report significant progress in vaccine development, including the completion of enrollment for two Phase 3 trials for its VAX-31 candidate and dosing the first participant in the Phase 1 study for VAX-A1.

Vaxcyte COO Jim Wassil Executes Stock Sale Under 10b5-1 Plan Amid Vaccine Development Milestones
PCVX

Key Points

  • Biotechnology
  • Pharmaceuticals
  • Healthcare

Jim Wassil, Chief Operating Officer of Vaxcyte, Inc. (NASDAQ:PCVX), conducted stock sales totaling $111,415 on June 1, 2026. According to an SEC filing, the COO sold a total of 2,250 shares of common stock. These transactions were structured under a pre-arranged Rule 10b5-1 trading plan that had been adopted on December 9, 2025.

The weighted-average selling price for these shares ranged between $49.404 and $50.257 per share. The total value realized from the disposal of the 2,250 shares was reported as $111,415. The sales were comprised of two distinct transactions. In the first instance, Mr. Wassil sold 1,949 shares at a weighted-average price of $49.404 per share. The stated price for this initial lot represents a weighted average derived from various sale prices within a defined range. Separately, a second transaction accounted for the disposition of 301 shares, which were sold at a weighted-average price of $50.257 per share, also reflecting a weighted average across multiple sales.

Following these recent divestitures, Mr. Wassil's direct holdings in Vaxcyte common stock amount to 158,494 shares. While the company's current trading price is reported at $46.97, representing a 7% decline over the preceding week, the stock has shown considerable appreciation, having gained nearly 37% over the past year.


Beyond the insider activity, Vaxcyte Inc. remains active in its vaccine development pipeline and commercial visibility. The company reported achieving enrollment completion for two critical Phase 3 clinical trials concerning its 31-valent pneumococcal conjugate vaccine candidate, designated VAX-31. Specifically, the OPUS-1 trial involved a cohort of approximately 4,000 participants, while the OPUS-2 trial enrolled around 1,300 participants. These ongoing studies are designed to gather data supporting a planned Biologics License Application submission to the U.S. Food and Drug Administration (FDA).

Furthermore, Vaxcyte publicized findings from its VAX-31 Phase 1/2 study in the journal

Risks

  • Regulatory hurdles
  • Market volatility

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