Stock Markets June 10, 2026 10:50 AM

TD Cowen Flags Short Interest Movements in Life Science Tools and Diagnostics Names

May 29 snapshot shows modest rises in short positions for select firms and larger declines for others across the sector

By Jordan Park
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XGN WAT AVTR MYGN TXG

TD Cowen published a May 29 snapshot of short interest in life science tools and diagnostics stocks, documenting small upticks in short positions for several companies and larger reductions for others. Exagen, Waters, Avantor and Myriad registered the biggest increases, while 10X Genomics, Pacific Biosciences, Tempur Sealy, GRAIL and Qiagen posted the largest declines. TD Cowen also identified four names with the highest overall short interest within the group.

TD Cowen Flags Short Interest Movements in Life Science Tools and Diagnostics Names
XGN WAT AVTR MYGN TXG
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Key Points

  • TD Cowen published short interest figures for life science tools and diagnostics stocks as of May 29.
  • Exagen (XGN), Waters (WAT), Avantor (AVTR), and Myriad Genetics (MYGN) recorded the largest increases in short interest, with no single increase exceeding 0.6% of shares outstanding.
  • 10X Genomics (TXG), Pacific Biosciences (PACB), Tempur Sealy (TEM), GRAIL (GRAL), and Qiagen (QGEN) saw the largest declines; Tempur Sealy, Pacific Biosciences, GeneDx (WGS) and GRAIL were the most heavily shorted names.

TD Cowen released data on short interest in a group of life science tools and diagnostics companies as of May 29, with the information published on Tuesday. The dataset highlights where investors have been increasing or decreasing their short exposure within the sector.

Among the stocks tracked, Exagen Inc. (NASDAQ:XGN), Waters Corp. (NYSE:WAT), Avantor Inc. (NYSE:AVTR), and Myriad Genetics Inc. (NASDAQ:MYGN) registered the largest increases in short interest during the reporting period. TD Cowen noted that none of those increases amounted to more than 0.6% of shares outstanding.

On the other side of the ledger, the largest declines in short interest were observed at 10X Genomics Inc. (NASDAQ:TXG), Pacific Biosciences of California Inc. (NASDAQ:PACB), Tempur Sealy International Inc. (NYSE:TEM), GRAIL Inc. (NASDAQ:GRAL), and Qiagen N.V. (NYSE:QGEN).

TD Cowen also singled out the names carrying the heaviest short positions within the cohort. The four most heavily shorted names identified were Tempur Sealy International, Pacific Biosciences, GeneDx Holdings Corp. (NASDAQ:WGS), and GRAIL.

Short interest is defined as the number of shares that have been sold short and remain open - that is, sold but not yet covered or closed out. The figures provided by TD Cowen therefore represent a snapshot of outstanding short positions at the specified date.

The report presents a cross-section of short interest activity across the life science tools and diagnostics sector. It documents both marginal increases in short exposure for certain names and more pronounced reductions for others, as well as identifying which companies held the largest outstanding short positions at the time of the snapshot.


Methodological note: The data reflect short interest as of May 29 and were published by TD Cowen on Tuesday. The numbers cited are limited to the sample of stocks included in TD Cowen's release and represent that specific reporting date.

Risks

  • The dataset is a snapshot as of May 29 and reflects only outstanding short positions at that date, limiting its ability to capture subsequent activity or trends.
  • Because none of the reported increases exceeded 0.6% of shares outstanding, the magnitude of short-position changes in some names was modest, which may constrain interpretations of market sentiment from this release.

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