Press Releases August 18, 2026 04:15 PM

Silo Pharma Receives Notice of Allowance for Canadian Patent Application for Novel PTSD Treatment

Silo Pharma Secures Canadian Patent Allowance for PTSD Treatment, Expanding Global Intellectual Property Protection

By Sofia Navarro
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Silo Pharma announced that the Canadian Intellectual Property Office has issued a Notice of Allowance for its patent application covering SPC-15, an intranasal 5-HT4 receptor agonist targeting PTSD and stress-induced psychiatric disorders. This follows a recent European patent grant, strengthening the company’s global IP portfolio for SPC-15. The company holds exclusive global licensing rights through Columbia University and plans to leverage the FDA’s 505(b)(2) pathway to streamline development.

Silo Pharma Receives Notice of Allowance for Canadian Patent Application for Novel PTSD Treatment
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Key Points

  • Canadian patent allowance for SPC-15 enhances Silo Pharma's international IP protection alongside a granted European patent, supporting commercialization efforts globally.
  • SPC-15 targets PTSD and stress-related psychiatric disorders using an intranasal serotonin 4 receptor agonist, addressing a significant unmet medical need.
  • Silo Pharma plans to utilize the FDA’s efficient 505(b)(2) regulatory pathway, potentially reducing development time and costs for SPC-15.
  • The announcement impacts biotechnology and pharmaceutical sectors, focusing on mental health therapeutics and drug development technologies.

Follows recent European patent grant and coverage in multiple international markets as Silo continues to strengthen licensed IP portfolio for lead therapeutic program

SARASOTA, FLA., Aug. 18, 2026 (GLOBE NEWSWIRE) -- Silo Pharma (Nasdaq: SILO) (“Silo” or “the Company”), a developmental-stage biopharmaceutical company focused on novel therapeutics and drug delivery systems with a wholly owned managed AI agent platform subsidiary, today announced that the Canadian Intellectual Property Office (CIPO) has issued a Notice of Allowance for a patent application covering its lead asset, SPC-15, an intranasal 5-HT4 receptor agonist targeting post-traumatic stress disorder (PTSD) and other stress-induced psychiatric disorders. The Company has an exclusive license for the Canadian patent application as part of its broader license agreement with Columbia University to further develop, manufacture, and commercialize SPC-15 globally.

The allowed patent application, titled “Prophylactic Efficacy of Serotonin 4 Receptor Agonists Against Stress,” covers methods of preventing or delaying stress-induced fear and depressive-like behavior and methods for inducing and/or enhancing stress resilience by administering selected serotonin 4 (5-HT4) receptor agonists prior to a stressor. Corresponding intellectual property has been granted or is advancing in multiple international markets, including a recently granted European patent covering the same core invention.

“The Canadian patent allowance adds to our momentum in securing broad international protection for SPC-15,” said Eric Weisblum, Chief Executive Officer of Silo Pharma. “With corresponding claims receiving protection across multiple markets, we continue to strengthen the global IP position of SPC-15 and our broader therapeutic portfolio.”

Silo intends to utilize the FDA’s streamlined 505(b)(2) regulatory pathway for SPC-15, which could shorten clinical timelines and reduce development costs

About Silo Pharma, Inc.

Silo Pharma is a diversified developmental-stage biopharmaceutical company with a therapeutic focus on addressing underserved conditions, including stress-induced psychiatric disorders, chronic pain, and central nervous system (CNS) diseases. The Company’s portfolio includes innovative programs such as SPC-15 for post-traumatic stress disorder (PTSD), SP-26 for fibromyalgia and chronic pain, and a preclinical asset targeting Alzheimer’s disease. Silo’s research is conducted in collaboration with leading universities and laboratories. silopharma.com

QwikAgents, Silo Pharma's wholly owned artificial intelligence subsidiary, is a managed AI agent platform that delivers dedicated autonomous agents for research, content generation, scheduling, and workflow automation each running in a persistent environment with proprietary smart-routing across multiple AI models. The subsidiary reflects Silo's strategy to expand into high-growth technology markets while continuing to advance its core biopharmaceutical pipeline. qwikagents.com

Forward Looking Statements

This news release contains “forward-looking statements” within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. These statements are identified using words “could”, “believe”, “anticipate”, “intend”, “estimate”, “expect”, “may”, “continue”, “predict”, “potential”, and similar expressions that are intended to identify forward-looking statements. Such statements involve known and unknown risks, uncertainties, and other factors that could cause the actual results of the Company to differ materially from the results expressed or implied by such statements, including statements about changes to anticipated sources of revenues, future economic and competitive conditions, difficulties in developing the Company’s technology platforms, retaining and expanding the Company’s customer base, fluctuations in consumer spending on the Company’s products and other factors. Accordingly, although the Company believes that the expectations reflected in such forward-looking statements are reasonable, there can be no assurance that such expectations will prove to be correct. The Company disclaims any obligations to publicly update or release any revisions to the forward-looking information contained in this press release, whether as a result of new information, future events, or otherwise, after the date of this press release or to reflect the occurrence of unanticipated events except as required by law.

Contact

(800) 705-0120
[email protected]


Risks

  • The successful commercialization of SPC-15 depends on regulatory approvals, and there is uncertainty whether FDA or other agencies will grant necessary permissions under the 505(b)(2) pathway.
  • Market acceptance and competitive landscape in psychiatric disorder treatments could affect revenue potential and adoption of SPC-15.
  • Development-stage biopharmaceutical companies face financing and operational risks that may hinder progress or impact stock performance.

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