Insider Trading July 9, 2026 07:39 PM

Disc Medicine COO Jonathan Yu Executes Pre-Arranged Stock Sale

Executive divestment follows option exercise under Rule 10b5-1 plan as company advances clinical pipeline

By Hana Yamamoto
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IRON

Jonathan Yen-Wen Yu, Chief Operating Officer of Disc Medicine, Inc. (NASDAQ:IRON), executed a transaction involving the sale of 100 shares of the company's common stock on July 7, 2026. The shares were disposed of at a price of $82.50 each, resulting in a total transaction value of $8,250. This sale was part of a broader sequence of events that included the prior exercise of stock options. The current market price of the stock stands at $78.91, which is lower than the price at which Mr. Yu sold his shares. Despite this recent price movement, the stock has generated a 41% return over the past year. Market data indicates that Disc Medicine's stock exhibits high volatility, characterized by a beta of 2.07. Current analytical assessments suggest that the company's valuation may be elevated relative to its estimated Fair Value. The transaction was conducted under a pre-arranged Rule 10b5-1 trading plan adopted by Mr. Yu on March 17, 2026. Following this sale, Mr. Yu's direct holdings in Disc Medicine common stock total 54,324 shares. The stock options that were exercised to facilitate this transaction were part of a grant that vests in 48 equal monthly installments, beginning on December 29, 2022, and requiring continued service from Mr. Yu. After the exercise, Mr. Yu holds 23,747 derivative securities, specifically stock options. In parallel corporate developments, Disc Medicine presented updated clinical trial data for its investigational treatments at the European Hematology Association Annual Meeting. The RALLY-MF trial, which evaluated treatments for myelofibrosis and anemia, enrolled 61 adult patients, with 50 patients included in the responder analysis. Additionally, the company completed a Type A meeting with the U.S. Food and Drug Administration regarding a Complete Response Letter for bitopertin in the context of erythropoietic protoporphyria. The FDA indicated that the ongoing Phase 3 APOLLO study could potentially support a traditional approval if successful. Stifel reiterated a Buy rating and a $111.00 price target on Disc Medicine following the presentation of Phase 2 RALLY-MF trial data. Furthermore, Disc Medicine launched an expanded access program for bitopertin in the U.S. for patients with erythropoietic protoporphyria and X-linked protoporphyria, intended for eligible patients lacking satisfactory therapeutic alternatives.

Disc Medicine COO Jonathan Yu Executes Pre-Arranged Stock Sale
IRON
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Key Points

  • Jonathan Yen-Wen Yu, Chief Operating Officer of Disc Medicine, sold 100 shares at $82.50 each on July 7, 2026, under a pre-arranged Rule 10b5-1 plan.
  • The sale followed the exercise of stock options acquired at $13.50 per share, with vesting contingent on continued service over 48 months.
  • Disc Medicine presented updated RALLY-MF trial data and completed an FDA meeting, with Stifel reiterating a Buy rating and $111.00 price target.

Jonathan Yen-Wen Yu, serving as the Chief Operating Officer for Disc Medicine, Inc. (NASDAQ:IRON), has completed a transaction involving the disposition of 100 shares of the company's common stock. This sale took place on July 7, 2026, with the shares being sold at a price of $82.50 each, culminating in a total value of $8,250. The current trading price of the stock is recorded at $78.91, which represents a decline from the price at which Mr. Yu executed his sale. Despite this recent downward movement, the stock has delivered a 41% return over the past year. Market analysis indicates that Disc Medicine's stock exhibits high volatility, characterized by a beta of 2.07. Current assessments suggest that the company is overvalued relative to its Fair Value.

The sale was executed in conjunction with the exercise of stock options. Through this process, Mr. Yu acquired 100 shares of Disc Medicine common stock at a price of $13.50 per share, amounting to $1,350. Both the acquisition and the subsequent sale were carried out under a Rule 10b5-1 trading plan, which Mr. Yu adopted on March 17, 2026. Following these transactions, Mr. Yu directly holds 54,324 shares of Disc Medicine common stock. The stock options exercised were part of a grant where the underlying shares vest in 48 equal monthly installments following December 29, 2022, contingent on Mr. Yu’s continued service. After the exercise, Mr. Yu holds 23,747 derivative securities (stock options).

In other recent news, Disc Medicine Inc. presented updated clinical trial data for its investigational treatments at the European Hematology Association Annual Meeting. The RALLY-MF trial enrolled 61 adult patients with myelofibrosis and anemia, with 50 patients included in the responder analysis. Additionally, Disc Medicine completed a Type A meeting with the U.S. Food and Drug Administration regarding the Complete Response Letter for bitopertin in erythropoietic protoporphyria. The FDA agreed that the ongoing Phase 3 APOLLO study could potentially support a traditional approval if successful. Stifel reiterated a Buy rating and a $111.00 price target on Disc Medicine following the presentation of Phase 2 RALLY-MF trial data. Furthermore, Disc Medicine launched an expanded access program for bitopertin in the U.S. for patients with erythropoietic protoporphyria and X-linked protoporphyria. This program is intended for eligible patients who lack satisfactory therapeutic alternatives.

Risks

  • The stock exhibits high volatility with a beta of 2.07, indicating potential price fluctuations that could impact investor returns.
  • Current analysis suggests the company is overvalued relative to its Fair Value, which may pose a risk to future stock performance.
  • The success of the Phase 3 APOLLO study remains uncertain, as it is contingent on successful outcomes to support traditional approval.

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