Press Releases May 5, 2026 05:50 PM

Biomea Fusion Announces Poster Presentations of Icovamenib at the American Diabetes Association (ADA) 86th Scientific Sessions

Biomea Fusion announces promising late-breaking posters on icovamenib for diabetes at ADA 2026

By Caleb Monroe BMEA

Biomea Fusion, a clinical-stage company developing treatments for diabetes and obesity, announced the presentation of three late-breaking posters on their investigational oral menin inhibitor, icovamenib, at the ADA 86th Scientific Sessions. The data highlights icovamenib's potential to improve beta cell function and metabolic health in both type 1 and type 2 diabetes, underscoring its potential as a novel therapeutic approach.

Biomea Fusion Announces Poster Presentations of Icovamenib at the American Diabetes Association (ADA) 86th Scientific Sessions
BMEA

Key Points

  • Three late-breaking poster presentations related to icovamenib have been selected for the American Diabetes Association 86th Scientific Sessions.
  • Icovamenib is a Phase 2 investigational oral menin inhibitor targeting beta cell dysfunction in diabetes, showing potential to restore beta cell mass and improve insulin secretion.
  • The presentations cover glycemic improvements, endogenous insulin secretion, and mechanisms that support metabolic health in diabetes patients.
  • The diabetes and obesity sectors are directly impacted, with potential implications for pharmaceutical and biotech markets focused on metabolic disorders.

SAN CARLOS, Calif., May 05, 2026 (GLOBE NEWSWIRE) -- Biomea Fusion, Inc. (“Biomea” or “Biomea Fusion” or “the Company”) (Nasdaq: BMEA), a clinical-stage diabetes and obesity company, today announced that three icovamenib abstracts have been selected for late-breaking poster presentations at the American Diabetes Association (ADA) 86th Scientific Sessions, taking place June 5–8, 2026 in New Orleans. The presentations include data from icovamenib, the Company’s investigational oral menin inhibitor, across both type 1 and type 2 diabetes, highlighting its potential to improve beta cell function and support metabolic health.

Presentation Details

Title: Glycemic Improvements with Icovamenib in T2D on Background GLP-1 Therapy: COVALENT-111 Subgroup Analysis
Session: Late-Breaking Poster Session 2857-LB
Presenter: Juan Pablo Frías, M.D.
Date/Time: June 7, 2026, at 12:30 pm – 1:30 pm CT

Title: Icovamenib, a Menin Inhibitor, Improves Endogenous Insulin Secretion in Type 1 Diabetes: Results from the COVALENT-112 Study
Session: Late-Breaking Poster Session 2858-LB
Presenter: Juan Pablo Frías, M.D.
Date: June 7, 2026, at 12:30 pm – 1:30 pm CT

Title: Menin Inhibitor Icovamenib Activates Mechanisms That Support Metabolic Health
Session: Late-Breaking Poster Session 2871-LB
Presenter: Mini Balakrishnan, Ph.D.
Date/Time: June 7, 2026, at 12:30 pm – 1:30 pm CT

All presentations will be available following the lifting of the embargo on Friday, June 5, 2026, at 6:30 PM CT. At that time, materials will be published on the Diabetes® journal website and in the Investors & Media section of Biomea’s website.

About Icovamenib
Icovamenib is an orally administered investigational small molecule currently in Phase 2 clinical development for the treatment of diabetes. Icovamenib targets menin, a transcriptional regulator implicated in beta cell dysfunction, and has been shown in preclinical and clinical studies to induce transient reductions in menin protein levels in pancreatic islets, thereby modulating pathways associated with insulin secretion and glycemic control. Through this mechanism, icovamenib has the potential to restore beta cell mass and function and improve endogenous insulin production. As a potential short-course therapy, icovamenib could represent a novel treatment approach for patients with diabetes, particularly those who have not achieved adequate control with standard-of-care therapies.

About Biomea Fusion
Biomea Fusion is a clinical-stage diabetes and obesity medicines company focused on the development of its oral small molecule therapies, icovamenib and BMF-650, for diabetes and obesity. These programs target metabolic disorders, a global health challenge affecting nearly half of Americans and one-fifth of the world’s population. Biomea’s mission is to deliver transformative treatments that restore health for patients living with diabetes, obesity, and related conditions. We aim to cure.

Visit us at www.biomeafusion.com and follow us on LinkedIn, X and Facebook.

Contact:
Meichiel Jennifer Weiss
Sr. Director of Investor Relations and Corporate Development
[email protected]


Risks

  • Icovamenib is still in Phase 2 clinical development, meaning safety and efficacy outcomes are not yet fully established, presenting development and regulatory risks.
  • Efficacy in diverse patient populations and long-term benefits remain uncertain, which could affect commercial viability.
  • Competition in the diabetes therapeutics space is intense, and novel treatments face uncertainty in gaining market adoption and reimbursement.

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