InflaRx Reports Favorable Reactive Metabolite Profile for Izicopan in Human Liver Microsomes
InflaRx N.V. announced new preclinical data showing that izicopan, their investigational oral C5aR1 inhibitor, demonstrates minimal reactive metabolite formation in human liver microsomes, indicating a potentially safer bioactivation profile compared to the marketed drug avacopan. Izicopan has shown strong pharmacokinetic/pharmacodynamic and safety…