Press Releases June 30, 2026 04:05 PM

4DMT Announces Presentation at 44th Annual Scientific Meeting of the American Society of Retina Specialists

4D Molecular Therapeutics to Present 2-Year Follow-Up Data on Intravitreal Gene Therapy for Wet AMD at ASRS Annual Meeting

By Marcus Reed
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4D Molecular Therapeutics announced a podium presentation at the 44th Annual Scientific Meeting of the American Society of Retina Specialists, detailing 2-year follow-up data from its Phase 2b PRISM clinical trial evaluating 4D-150, an intravitreal gene therapy targeting neovascular age-related macular degeneration (AMD). The presentation underscores the company’s progress in developing durable gene therapies aimed at reducing treatment burden for retinal vascular diseases. 4D-150 is currently in Phase 3 development for wet AMD and diabetic macular edema.

4DMT Announces Presentation at 44th Annual Scientific Meeting of the American Society of Retina Specialists
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Key Points

  • 4DMT will present 2-year follow-up data from the PRISM Phase 2b trial evaluating 4D-150, its intravitreal gene therapy targeting neovascular AMD.
  • 4D-150 is designed to provide multi-year sustained delivery of anti-VEGF biologics, potentially reducing frequent injections currently required in retinal vascular diseases.
  • The presentation at a major retina specialists conference highlights the advancement of 4DMT’s lead product in addressing blinding retinal diseases and supports its ongoing Phase 3 development.
  • Sectors impacted include biotechnology, healthcare, ophthalmology, and genetic medicine markets.

EMERYVILLE, Calif., June 30, 2026 (GLOBE NEWSWIRE) -- 4D Molecular Therapeutics (Nasdaq: FDMT, 4DMT or the Company), a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics with potential to transform treatment paradigms and provide unprecedented benefits to patients, today announced a podium presentation at the 44th Annual Scientific Meeting of the American Society of Retina Specialists (ASRS) being held in Montreal, Canada, from July 15 - 18, 2026.

ASRS 2026 Presentation Details:

Title:2-Year Follow Up: PRISM Phase 2b Clinical Trial Evaluating
Investigational 4D-150, an Intravitreal Gene Therapy, in a
Broad Neovascular AMD PopulationDate/Time:Saturday, July 18, 2026 (2:58 – 3:01 p.m. ET)Presenter:Carl Awh, MD, FASRS, Tennessee Retina


The presentation will also be available on the 4DMT website: https://4dmoleculartherapeutics.com/pipeline/#posters-and-publications

About 4DMT  

4DMT is a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics with potential to transform treatment paradigms and provide unprecedented benefits to patients. The Company’s lead product candidate 4D-150 is designed to be a backbone therapy forming the foundation of treatment of blinding retinal vascular diseases by providing multi-year sustained delivery of anti-VEGF biologics (aflibercept and anti-VEGF-C) with a single intravitreal injection, which substantially reduces the treatment burden associated with current bolus injections. The Company’s lead indication for 4D-150 is wet age-related macular degeneration, which is currently in Phase 3 development, and second indication is diabetic macular edema. The Company’s second product candidate is 4D-710, which is the first known genetic medicine to demonstrate successful delivery and expression of the CFTR transgene in the lungs of people with cystic fibrosis after aerosol delivery. 4D Molecular Therapeutics™, 4DMT™, Therapeutic Vector Evolution™ and the 4DMT logo are trademarks of 4DMT.  

All of the Company’s product candidates are in clinical or preclinical development and have not yet been approved for marketing by the U.S. Food and Drug Administration or any other regulatory authority. No representation is made as to the safety or effectiveness of the Company’s product candidates for the therapeutic uses for which they are being studied. Learn more at www.4DMT.com and follow us on LinkedIn. 

Contacts:

Media:

Jenn Gordon
dna Communications
[email protected]

Investors:

Julian Pei
Head of Investor Relations and Strategic Finance
[email protected]


Risks

  • All product candidates including 4D-150 are still in clinical or preclinical stages and have not received regulatory approval, implying clinical and regulatory risks in demonstrating safety and efficacy.
  • The therapeutic uses are investigational, and no guarantee exists regarding market approval or commercial success, which may impact investor confidence.
  • Competition and potential market adoption risks exist in the retinal disease treatment sector, where other therapies and gene therapies are evolving rapidly.

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