Press Releases April 23, 2026 08:00 AM

Reviva to Participate in a Fireside Chat Hosted by A.G.P. on Brilaroxazine’s Potential Across Multiple Neuropsychiatric Indications

Reviva CEO to Discuss Brilaroxazine's Progress and Potential in Neuropsychiatric and Inflammatory Diseases at Upcoming A.G.P. Fireside Chat

By Jordan Park RVPH
Reviva to Participate in a Fireside Chat Hosted by A.G.P. on Brilaroxazine’s Potential Across Multiple Neuropsychiatric Indications
RVPH

Reviva Pharmaceuticals announced that its CEO, Laxminarayan Bhat, will participate in an A.G.P.-hosted fireside chat to discuss the clinical developments and upcoming milestones for brilaroxazine, a promising drug candidate targeting schizophrenia and other neuropsychiatric and inflammatory diseases. Positive Phase 3 data and orphan drug designation highlight the drug's potential.

Key Points

  • Phase 3 RECOVER trial showed brilaroxazine met all primary and secondary endpoints with significant symptom reduction in schizophrenia and an excellent safety profile.
  • Brilaroxazine holds orphan drug designation for pulmonary arterial hypertension and idiopathic pulmonary fibrosis, expanding potential therapeutic applications.
  • Upcoming discussion will focus on clinical, regulatory, and intellectual property milestones, reflecting strong pipeline progress and strategic focus on CNS, inflammatory, and cardiometabolic diseases.
  • Sectors impacted include biotechnology, pharmaceuticals, healthcare, and neuropsychiatric therapeutics.

CUPERTINO, Calif., April 23, 2026 (GLOBE NEWSWIRE) -- Reviva Pharmaceuticals Holdings, Inc. (NASDAQ: RVPH) (“Reviva,” the “Company” “we” or “us”), a late-stage pharmaceutical company developing therapies that seek to address unmet medical needs in the areas of central nervous system (CNS), inflammatory and cardiometabolic diseases, today announced that Laxminarayan Bhat, PhD, Founder, President, and CEO of Reviva, will participate in a fireside chat hosted by A.G.P. Equity Research Analyst James Molloy on Monday, April 27, 2026 at 11:00 AM ET.

The fireside chat will highlight the recent developments from Reviva’s clinical stage drug candidate brilaroxazine and upcoming clinical, regulatory, and IP milestones.

A.G.P. Fireside Chat
Format: Fireside Chat
Date: Monday, April 27, 2026
Time: 11:00 a.m. ET
Webcast Link: CLICK HERE

About Brilaroxazine
Brilaroxazine is an in-house discovered new chemical entity with potent affinity and selectivity against key serotonin and dopamine receptors implicated in the pathophysiology of several conditions including schizophrenia, psoriasis and interstitial lung diseases like pulmonary hypertension, pulmonary arterial hypertension (PAH) and idiopathic pulmonary fibrosis (IPF). Positive topline data from the global Phase 3 RECOVER trial in schizophrenia demonstrated the trial successfully met all primary and secondary endpoints with statistically significant and clinically meaningful reductions across all major symptom domains including reduction in key proinflammatory cytokines implicated in the pathophysiology of schizophrenia and comorbid inflammatory conditions at week 4 with 50 mg of brilaroxazine vs. placebo, with a generally well-tolerated side effect profile comparable to placebo and discontinuation rates lower than placebo. Positive data from a clinical drug-drug interaction (DDI) study investigating the potential effect of the CYP3A4 enzyme on brilaroxazine in healthy subjects supports no clinically significant interaction when combined with CYP3A4 inhibitors. Reviva believes that a full battery of regulatory compliant toxicology and safety pharmacology studies has been completed for brilaroxazine. Reviva intends to develop brilaroxazine for other neuropsychiatric indications including bipolar disorder, major depressive disorder (MDD) and attention-deficit/hyperactivity disorder (ADHD).

Additionally, brilaroxazine has shown promising nonclinical activity for inflammatory diseases psoriasis, pulmonary arterial hypertension (PAH) and idiopathic pulmonary fibrosis (IPF) with mitigation of fibrosis and inflammation in translational animal models. Brilaroxazine has already received Orphan Drug Designation by the FDA for the treatment of PAH and IPF conditions. To learn more about the clinical and preclinical data available for brilaroxazine, please visit revivapharma.com/publications.

About Reviva 
Reviva is a late-stage biopharmaceutical company that discovers, develops, and seeks to commercialize next-generation therapeutics for diseases representing unmet medical needs and burdens to society, patients, and their families. Reviva’s current pipeline focuses on the central nervous system (CNS), inflammatory and cardiometabolic diseases. Reviva’s pipeline currently includes two drug candidates, brilaroxazine (RP5063) and RP1208. Both are new chemical entities discovered in-house. Reviva has been granted composition of matter patents for both brilaroxazine and RP1208 in the United States, Europe, and several other countries.

Corporate Contact:
Reviva Pharmaceuticals Holdings, Inc.
Laxminarayan Bhat, PhD 
www.revivapharma.com

Investor Relations Contact:
LifeSci Advisors, LLC
PJ Kelleher
[email protected]


Risks

  • Clinical and regulatory risks remain as brilaroxazine progresses through the approval process for new indications beyond schizophrenia.
  • Market acceptance and reimbursement for brilaroxazine in multiple indications are uncertain, impacting commercial viability.
  • Competition from existing and emerging therapies in CNS and inflammatory disease markets could limit market share and revenue growth.

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