Press Releases April 22, 2026 08:00 AM

Immutep Announces Abstract Accepted for Presentation at the American Society of Clinical Oncology (ASCO) 2026 Annual Meeting

Immutep's eftilagimod alfa shows promising immune activation and survival benefits in metastatic cancer, featured at ASCO 2026

By Hana Yamamoto IMMP
Immutep Announces Abstract Accepted for Presentation at the American Society of Clinical Oncology (ASCO) 2026 Annual Meeting
IMMP

Immutep Limited announces that a clinical abstract on its immunotherapy drug eftilagimod alfa has been accepted for poster presentation at the ASCO 2026 Annual Meeting. The data highlights the drug’s ability to activate lymphocytes rapidly and sustain immune response, with markers correlating to improved overall survival in metastatic cancer patients. This supports the clinical relevance of eftilagimod alfa's mechanism as an antigen-presenting cell activator targeting MHC Class II.

Key Points

  • The abstract details cumulative clinical data showing eftilagimod alfa induces rapid and sustained lymphocyte activation in metastatic cancer patients.
  • Immune activation markers linked to improved overall survival suggest promising therapeutic potential of eftilagimod alfa.
  • Presentation at ASCO 2026, the leading oncology conference, enhances visibility and credibility of Immutep’s immunotherapy programs.

SYDNEY, AUSTRALIA, April 22, 2026 (GLOBE NEWSWIRE) -- Immutep Limited (ASX: IMM; NASDAQ: IMMP) (“Immutep” or “the Company”), a clinical-stage immunotherapy company targeting cancer and autoimmune diseases, today announces an abstract has been selected for poster presentation at the upcoming 2026 American Society of Clinical Oncology’s (ASCO) Annual Meeting, taking place in-person and online from 29 May-2 June 2026 in Chicago, Illinois (United States).

The accepted abstract, titled “Impact of eftilagimod alfa, an APC activator via MHC class II, on lymphocyte activation and survival outcomes in metastatic cancer patients,” will be presented within the Developmental Therapeutics—Immunotherapy sessions by Professor Martin Forster from the UCL Cancer Institute, UK.

The poster will present cumulative clinical and translational data demonstrating that eftilagimod alfa (efti), an antigen-presenting cell (APC) activator targeting MHC Class II, induces rapid and sustained lymphocyte activation. Across multiple late-stage cancer studies1, immune activation markers were associated with improved overall survival outcomes in patients with metastatic disease, supporting the clinical relevance of eftilagimod alfa’s mechanism of action.

ASCO 2026 Poster Presentation Details

Title: Impact of eftilagimod alfa, an APC activator via MHC class II, on lymphocyte activation and survival outcomes in metastatic cancer patients
Poster Session: Developmental Therapeutics—Immunotherapy
Date and Time: 30 May 2026, 1:30 PM-4:30 PM CDT
Poster Board: 359
Abstract #: 2569

About ASCO 2026

The ASCO Annual Meeting represents the world’s largest gathering of oncology physicians, industry representatives, researchers, patient advocates and investment analysts to discuss cutting-edge clinical research and emerging therapeutics in oncology, and to gain insights to improve cancer care. More than 40,000 attendees from around the world are expected to participate in person and online to stay up to date on the latest advances across all areas of cancer research and to hear real-time insights from world-renowned experts. For additional information on the ASCO Annual Meeting, please visit www.asco.org.

About Immutep

Immutep is a clinical-stage biotechnology company developing novel immunotherapies for cancer and autoimmune diseases. The Company is a pioneer in the understanding and advancement of therapeutics related to Lymphocyte Activation Gene-3 (LAG-3), and its diversified product portfolio harnesses LAG-3’s ability to stimulate or suppress the immune response. Immutep is dedicated to leveraging its expertise to bring innovative treatment options to patients in need and to maximise value for shareholders. For more information, please visit www.immutep.com.

Australian Investors/Media:
Eleanor Pearson, Sodali & Co.
+61 2 9066 4071; [email protected]

U.S. Investors/Media:
Matthew Beck, astr partners
+1 (917) 415-1750; [email protected]

This announcement was authorised for release by the CEO of Immutep Limited.

1 Please note that the abstract does not include data from the TACTI-004 study, as immune data collection for that trial has not yet been completed. All data presented were collected from earlier clinical trials, initiated prior to TACTI-004.


Risks

  • Data presented does not include results from the ongoing TACTI-004 study, meaning full clinical validation is pending.
  • As a clinical-stage biotech, Immutep's therapies remain subject to clinical trial risks and regulatory approvals.
  • The immunotherapy market is highly competitive, and clinical outcomes may vary with larger patient populations or further studies.

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