Press Releases April 9, 2026 08:00 PM

Allogene Therapeutics to Announce Interim Futility Analysis Data from its Pivotal Phase 2 ALPHA3 Trial with Cemacabtagene Ansegedleucel (Cema-Cel) in First-Line Consolidation LBCL on Monday, April 13, 2026

Allogene to Present Interim Futility Analysis Data From Phase 2 ALPHA3 Trial in 1L LBCL

By Marcus Reed ALLO
Allogene Therapeutics to Announce Interim Futility Analysis Data from its Pivotal Phase 2 ALPHA3 Trial with Cemacabtagene Ansegedleucel (Cema-Cel) in First-Line Consolidation LBCL on Monday, April 13, 2026
ALLO

Allogene Therapeutics announced it will present interim futility analysis data from its pivotal Phase 2 ALPHA3 trial involving cemacabtagene ansegedleucel (cema-cel), aimed at first-line consolidation therapy in large B-cell lymphoma (LBCL), via a webcast on April 13, 2026.

Key Points

  • The interim futility analysis is part of a pivotal, randomized Phase 2 trial of an allogeneic CAR T therapy in LBCL patients.
  • The trial investigates cema-cel for first-line consolidation treatment, potentially impacting treatment options in oncology.
  • Allogene’s allogeneic CAR T products aim to provide off-the-shelf cell therapies to improve availability and scalability compared to autologous therapies.

SOUTH SAN FRANCISCO, Calif., April 10, 2026 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T) products for cancer and autoimmune disease, today announced the Company will host a conference call and webcast to review the interim futility analysis from its pivotal, randomized Phase 2 ALPHA3 trial with cemacabtagene ansegedleucel (cema-cel) in first-line (1L) consolidation large B-cell lymphoma (LBCL) on Monday, April 13, 2026.

The live conference call and webcast will take place at 5:30 a.m. PT / 8:30 a.m. ET. Please use this link to register. The webcast will be made available on the Company's website at www.allogene.com under the Investors tab in the News and Events section.

About Allogene Therapeutics
Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T) products for cancer and autoimmune disease. Led by cell therapy veterans applying proven CAR T experience, Allogene is developing a pipeline of “off-the-shelf” CAR T cell product candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients. For more information, please visit www.allogene.com, and follow Allogene Therapeutics on X and LinkedIn.

Allogene Media/Investor Contact:
Christine Cassiano
EVP, Chief Corporate Affairs & Brand Strategy Officer
[email protected]


Risks

  • Interim futility analysis could indicate lack of efficacy, potentially delaying or halting the trial and impacting future development timelines.
  • Clinical trial results inherently carry risks of adverse events or insufficient therapeutic benefit, affecting regulatory approval chances.
  • Market adoption depends on successful trial outcomes and competitive landscape in oncology cell therapies, impacting commercial potential.

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