Stock Markets August 4, 2026 06:58 AM

Pfizer nudges up revenue outlook after second-quarter earnings beat led by Eliquis

Company posts stronger-than-expected adjusted profit as Eliquis demand supports guidance; Metsera acquisition and newer drugs remain focal points for future growth

By Leila Farooq
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On Aug. 4, Pfizer reported second-quarter adjusted earnings that surpassed analyst expectations, driven by robust demand for the blood thinner Eliquis. The company slightly raised the lower end of its full-year sales forecast and highlighted its strategy to rely more on newer medicines and the $10 billion Metsera acquisition to diversify revenue away from waning COVID-related sales and aging blockbusters.

Pfizer nudges up revenue outlook after second-quarter earnings beat led by Eliquis
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Key Points

  • Pfizer beat second-quarter adjusted earnings expectations with $0.77 per share versus $0.68 expected, per LSEG.
  • The company raised the lower bound of its full-year sales forecast to $60.5 billion from $59.5 billion while keeping the upper bound at $62.5 billion.
  • Strategic focus on newer medicines and the $10 billion Metsera acquisition aims to reduce reliance on fading COVID revenue and aging blockbusters; investors will monitor execution and growth after 2028.

On Aug. 4, Pfizer slightly increased the low end of its full-year revenue projection after reporting second-quarter adjusted earnings that topped Wall Street estimates, led by strong demand for the blood thinner Eliquis. The stock reacted positively in premarket trading, rising 1.8% to $25.5.

Management continues to pursue a strategy that leans on newly launched medicines to compensate for declining COVID-related sales and to reduce dependence on older, established blockbusters. Investors are watching closely to see whether the company's $10 billion acquisition of Metsera will translate into a significant foothold in the rapidly expanding obesity treatment market.

For the full year, Pfizer now anticipates sales between $60.5 billion and $62.5 billion, an upward revision to the lower bound from the prior $59.5 billion to $62.5 billion range. The company reported adjusted earnings of $0.77 per share for the quarter, compared with analysts' estimates of $0.68 per share, based on data compiled by LSEG.

While the quarterly beat and the modestly improved guidance provided some near-term support for the stock, the company faces the backdrop of a share price that remains well below its pandemic-era highs - shares have fallen more than 50% from that peak. Pfizer has signaled expectations of a stronger growth trajectory returning after 2028.

The mix of results and strategic priorities underlines the balancing act for the drugmaker: sustaining revenue momentum from current franchise drugs like Eliquis while integrating acquisitions and newer products to reshape its portfolio over the coming years. How effectively Metsera contributes to that effort, and the pace at which newer medicines offset fading COVID revenue, will be key metrics investors track.


Market reaction: Shares rose 1.8% to $25.5 in premarket trading following the earnings release.

Reported results: Adjusted profit of $0.77 per share versus analyst expectations of $0.68 per share, according to LSEG. Revised full-year sales outlook to $60.5 billion - $62.5 billion from $59.5 billion - $62.5 billion.

Risks

  • Execution risk that the Metsera acquisition may not establish a meaningful presence in the obesity market as investors hope - impacts healthcare and biotech sectors.
  • Uncertainty around the pace at which newer medicines can offset declining COVID-related revenue and revenue from aging blockbusters - impacts pharmaceuticals and broader equity markets.
  • Persistently depressed share price - more than 50% below pandemic-era peak - could reflect investor caution about growth prospects and strategic execution.

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