Press Releases May 19, 2026 08:30 AM

Orchestra BioMed to Participate in the Jefferies Global Healthcare Conference

Orchestra BioMed to engage with investors at Jefferies Global Healthcare Conference highlighting innovative cardiovascular therapies

By Priya Menon OBIO

Orchestra BioMed announced its participation in the upcoming Jefferies Global Healthcare Conference, featuring CEO David Hochman in a fireside chat and one-on-one investor meetings. The company is advancing two flagship product candidates, AVIM Therapy for hypertension and Virtue Sirolimus AngioInfusion Balloon for atherosclerotic artery disease, both with FDA Breakthrough Device Designations and significant market potential. Strategic collaboration with Medtronic supports development and commercialization efforts, underscoring the company's growth prospects in the cardiovascular medical device sector.

Orchestra BioMed to Participate in the Jefferies Global Healthcare Conference
OBIO

Key Points

  • Orchestra BioMed will participate in the Jefferies Global Healthcare Conference with leadership engaging investors through a live webcast and meetings.
  • Two flagship therapies, AVIM Therapy for hypertension and Virtue SAB for artery disease, are in pivotal clinical trials with FDA Breakthrough Device Designations.
  • Strategic partnership with Medtronic enhances the development and commercialization potential of AVIM Therapy for a large patient population with unmet needs.

NEW HOPE, Pa., May 19, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, “Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patients through risk-reward sharing partnerships, today announced that company management will be participating in the Jefferies Global Healthcare Conference.

Chairman and CEO David Hochman will participate in a fireside chat with Matt Taylor, Managing Director at Jefferies at 9:55am ET on Thursday June 4, 2026 and will also host one-on-one meetings with investors that day and on Wednesday, June 3. The fireside chat will be accessible to investors and interested parties via a live webcast, which is available on Orchestra BioMed’s Investor Relations website.

About Orchestra BioMed
Orchestra BioMed is a biomedical innovation company accelerating high-impact technologies to patients through strategic collaborations with market-leading global medical device companies. The Company’s two flagship product candidates - Atrioventricular Interval Modulation (AVIM) Therapy and Virtue® Sirolimus AngioInfusion™ Balloon (Virtue SAB) - are currently undergoing pivotal clinical trials for their lead indications, each representing multi-billion-dollar annual global market opportunities. AVIM Therapy is a bioelectronic treatment for hypertension, the leading risk factor for death worldwide, and is designed to be delivered by a pacemaker and achieve immediate, substantial and sustained reductions in blood pressure in patients with hypertensive heart disease. The Company has a strategic collaboration with Medtronic, one of the largest medical device companies in the world and the global leader in cardiac pacing therapies, for the development and commercialization of AVIM Therapy for the treatment of uncontrolled hypertension in pacemaker-indicated patients. AVIM Therapy has FDA Breakthrough Device Designations for these patients, as well as an estimated 7.7 million total patients in the U.S. with uncontrolled hypertension despite medical therapy and increased cardiovascular risk. Virtue SAB is a highly differentiated, first-of-its-kind non-coated drug delivery angioplasty balloon system designed to deliver a large liquid dose of proprietary extended-release formulation of sirolimus, SirolimusEFR™, for the treatment of atherosclerotic artery disease, the leading cause of mortality worldwide. Virtue SAB has been granted Breakthrough Device Designation by the FDA for the treatment of coronary in-stent restenosis, coronary small vessel disease and below-the-knee peripheral artery disease. For further information about Orchestra BioMed, please visit www.orchestrabiomed.com, and follow us on LinkedIn.

Investor Contact:
Silas Newcomb
Orchestra BioMed
[email protected]

Media Contact:
Kelsey Kirk
Orchestra BioMed
484-682-4892
[email protected]


Risks

  • Clinical trial outcomes for AVIM Therapy and Virtue SAB remain uncertain and could affect regulatory approvals and commercialization timelines.
  • Dependence on the partnership with Medtronic introduces risk if collaboration terms or execution falter, impacting product development.
  • Regulatory hurdles and market adoption challenges in the highly competitive cardiovascular device sector may affect the company's growth and revenue projections.

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