Stock Markets May 15, 2026 11:52 AM

Acting Head of FDA Drug Center Expected to Depart After Commissioner’s Resignation

Tracey Beth Hoeg's potential exit follows a stalled overhaul of the childhood immunization schedule and wider management changes at HHS

By Marcus Reed

Tracey Beth Hoeg, the acting director of the U.S. Food and Drug Administration’s drug center, is expected to leave the agency days after FDA Commissioner Marty Makary resigned. Hoeg, an epidemiologist and sports physician who questioned COVID-19 vaccines during the pandemic, helped drive an initiative in January to cut the recommended childhood vaccine doses from 17 to 11. That schedule change is currently paused as part of a lawsuit concerning vaccine policy revisions under Health Secretary Robert F. Kennedy. HHS declined to comment on personnel matters.

Acting Head of FDA Drug Center Expected to Depart After Commissioner’s Resignation

Key Points

  • Tracey Beth Hoeg, acting head of the FDAs drug center, is expected to leave the agency days after Commissioner Marty Makary resigned - sectors affected include healthcare and government.
  • Hoeg, an epidemiologist and sports physician who raised doubts about COVID vaccines during the pandemic, led an initiative to cut the recommended childhood vaccine doses from 17 to 11 in January - impacting public health and pharmaceutical policy areas.
  • The childhood vaccine schedule changes have been paused because of a lawsuit contesting the broader overhaul of vaccine policies under Health Secretary Robert F. Kennedy - relevant to legal and regulatory sectors.

Officials familiar with internal planning say Tracey Beth Hoeg, the acting director of the U.S. Food and Drug Administrations drug center, is anticipated to depart the agency only days after the resignation of FDA Commissioner Marty Makary.

Hoeg, who is trained as an epidemiologist and sports physician, has been a prominent figure in recent policy discussions at the agency. During the COVID-19 pandemic she publicly cast doubt on COVID vaccines, and in January she played a leading role in efforts to revise the U.S. childhood immunization schedule. That initiative reduced the number of recommended childhood shots from 17 to 11.

Those proposed changes to the childhood vaccine schedule are not moving forward at this time. Officials say the adjustments were placed on hold in connection with a lawsuit that challenges the broader overhaul of vaccine policies being advanced under Health Secretary Robert F. Kennedy.

Asked for comment, HHS pointed to a standard response on staffing matters. "HHS and FDA do not comment on personnel matters," HHS spokeswoman Emily Hilliard said in a statement. The decision to remove Hoeg from her post, while widely expected inside the agency, has not been finalized, and Hoeg was not immediately available for comment.

The anticipated exit would coincide with a broader reorganization at the Department of Health and Human Services. The White House has reportedly increased its involvement with the department in recent months. Observers note that public opinion polls indicate Health Secretary Kennedy's efforts to alter U.S. vaccine policy could carry political costs ahead of the November midterm elections, which will determine whether Republicans keep control of Congress.

As planning continues within the agency and the department, the timing and finality of any personnel moves remain subject to change, according to sources familiar with the matter.

Risks

  • Uncertainty around leadership changes at the FDA and HHS could delay regulatory decision-making and policy implementation - affects healthcare and pharmaceutical markets.
  • The lawsuit that has put the childhood vaccine schedule revisions on hold creates legal and policy uncertainty that may affect vaccine manufacturers and public health planning - impacts pharmaceutical and public health sectors.
  • Increased White House involvement in HHS and polling that suggests vaccine policy changes could be politically costly introduce political risk ahead of the November midterm elections - affects government policy stability.

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