Press Releases September 9, 2026 08:00 AM

IN8bio Appoints Oxana Polyakova, Ph.D., as Senior Vice President of Research & Development

IN8bio Enhances Leadership with Appointment of γδ T Cell Expert Dr. Oxana Polyakova to Accelerate Development of Novel Immunotherapies

By Nina Shah
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IN8bio, a clinical-stage biopharmaceutical company focused on γδ T cell therapies, has appointed Dr. Oxana Polyakova as Senior Vice President of Research & Development. Dr. Polyakova brings two decades of expertise in γδ T cell biology and T cell engager therapeutics, strengthening IN8bio's leadership as they advance their pipeline targeting oncology and autoimmune diseases. Her appointment is expected to accelerate the development of IN8bio's novel T cell engager platform toward clinical applications.

IN8bio Appoints Oxana Polyakova, Ph.D., as Senior Vice President of Research & Development
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Key Points

  • Dr. Oxana Polyakova, a recognized leader in γδ T cell biology and T cell engagers, joins IN8bio as SVP R&D, bringing 20 years of drug discovery experience.
  • IN8bio's pipeline includes γδ T cell engager INB-600 and cell therapy candidates aimed at oncology and autoimmune diseases.
  • This leadership addition aims to accelerate clinical development and expand therapeutic applications of IN8bio's novel immunotherapy platforms.
  • The biotechnology, immunotherapy, oncology, and autoimmune disease sectors are directly impacted by advancements in γδ T cell therapies.

Renowned γδ T cell and T cell engager (TCE) expert brings two decades of drug discovery and development experience to IN8bio

Appointment strengthens IN8bio’s leadership and domain expertise as they advance their novel γδ T cell engager platform

NEW YORK, Sept. 09, 2026 (GLOBE NEWSWIRE) -- IN8bio, Inc. (Nasdaq: INAB), a clinical-stage biopharmaceutical company developing innovative gamma-delta (γδ) T cell therapies and T cell engagers for cancer and autoimmune diseases, today announced the appointment of Oxana Polyakova, Ph.D., as Senior Vice President of Research & Development. Dr. Polyakova is a recognized leader in γδ T cell biology and the discovery and development of γδ T cell engagers (TCEs), with 20 years of experience spanning oncology, immunology, cell therapies, antibodies and engager-based therapeutics.

Dr. Polyakova joins IN8bio from LAVA Therapeutics, a clinical-stage immuno-oncology company developing bispecific γδ T cell engagers, where she served as Chief Scientific Officer. She previously served as Chief Scientific Officer at LIfT Biosciences, a biotechnology company developing a first-in-class neutrophil-based therapy for the treatment of solid tumors, deepening her expertise in innate immunity. She was Scientific Founder and Head of Discovery at Adaptate Biotherapeutics, a γδ TCE focused spinout of GammaDelta Therapeutics, which was acquired by Takeda. At Adaptate, she designed and led its R&D strategy, established its laboratories and built its R&D team. Prior to Adaptate, Dr. Polyakova served as the Protein and Molecular Leader at GammaDelta Therapeutics. Early in her career, she held scientific and R&D leadership positions at Kesios Therapeutics, Immunocore and GlaxoSmithKline (now GSK).

“Oxana is one of the leading scientific minds in γδ T cell biology, with deep expertise in γδ T cell engagers,” said Lawrence Lamb, Ph.D., Chief Scientific Officer and co-founder of IN8bio. “Her experience and success translating novel γδ T cell biology into therapeutic programs makes her an exceptional addition to our leadership team. We have enjoyed working with Oxana over the past year and welcome her full-time as we advance our TCE pipeline towards the clinic. Oxana’s expertise will be instrumental in accelerating the development of a new generation of γδ T cell-based therapies for patients.”

“IN8bio is a leading company in γδ T cells that has a differentiated understanding of its biology and how these cells can be harnessed to attack cancer and autoimmune disease,” said Dr. Polyakova. “I have spent much of my career exploring the unique therapeutic potential of γδ T cells, including both T cell engagers and cell-based therapies. I am excited to join IN8bio at this stage of its evolution and to work to advance their novel γδ TCE platform into the clinic and to new indications that have the potential to meaningfully improve outcomes for patients.”

In her new role, Dr. Polyakova will help lead IN8bio’s research and development strategy, with a particular focus on strengthening and accelerating the Company’s T cell engager programs and expanding the potential of its platform across therapeutic areas in autoimmune and oncology.

About IN8bio

IN8bio is a clinical-stage biopharmaceutical company developing γδ T cell and γδ T cell engager (TCE) product candidates to address unmet medical needs. γδ T cells are a specialized population of T cells that possess unique properties, including the ability to differentiate between healthy and diseased tissue. The Company’s pipeline is anchored by INB-600, a novel γδ T cell engager platform with potential applications across oncology and autoimmune indications. IN8bio is also advancing INB-100, an allogeneic γδ T cell candidate for adult patients with high-risk leukemias undergoing haploidentical stem cell transplantation, and INB-200/400, an autologous genetically modified γδ T cell candidate for newly diagnosed glioblastoma (GBM). For more information about IN8bio, visit www.IN8bio.com.

Investors and Corporate Contact:

IN8bio, Inc.
Patrick McCall
646.933.5603
[email protected]

Media Contact
Kimberly Ha
KKH Advisors
917.291.5744
[email protected]

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/fe724a34-a144-448e-81c3-f14ca2105673


Risks

  • Clinical and regulatory risks inherent in developing novel γδ T cell-based therapies including CAR T and engager platforms may delay or hinder product approval and commercialization.
  • Competition in the immuno-oncology space from established and emerging biotech firms developing alternative cell therapies and T cell engager technologies could limit market share.
  • Uncertainties related to clinical trial outcomes, scalability, and manufacturing of complex biological products could impact IN8bio's development timelines and financial performance.

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