Press Releases September 9, 2026 07:00 AM

Eledon Pharmaceuticals Announces Presentation at the International Congress of The Transplantation Society

Eledon Pharmaceuticals to present long-term Phase 2 trial results for tegoprubart at international transplant conference

By Avery Klein
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Eledon Pharmaceuticals announced an upcoming oral presentation at the International Congress of The Transplantation Society showcasing long-term safety and efficacy data of its lead investigational drug, tegoprubart, for preventing kidney transplant rejection. The data come from the Phase 2 BESTOW trial and its extension, highlighting the drug's potential as a novel immunomodulatory therapy in transplantation.

Eledon Pharmaceuticals Announces Presentation at the International Congress of The Transplantation Society
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Key Points

  • Presentation of Phase 2 BESTOW trial and extension results focusing on tegoprubart's safety and efficacy in preventing kidney transplant rejection.
  • Tegoprubart is an anti-CD40L antibody targeting a well-validated immune pathway, aimed at non-lymphocyte depleting immunosuppression.
  • Eledon is exploring tegoprubart's potential across multiple transplantation types and other immune-mediated conditions like ALS.

IRVINE, Calif., Sept. 09, 2026 (GLOBE NEWSWIRE) -- Eledon Pharmaceuticals, Inc. (“Eledon”) (Nasdaq: ELDN) today announced an oral presentation highlighting the long-term safety and efficacy of tegoprubart in preventing kidney transplant rejection will take place at the upcoming International Congress of The Transplantation Society in Sydney, Australia, from September 20–23, 2026.

Details of the presentation are below:

Oral Presentation

Title: Phase 2 BESTOW trial and the BESTOW EXTENSION: Evaluating the long-term safety and efficacy of tegoprubart in preventing kidney transplant rejection

Presenter: Andrew Adams, M.D., Ph.D., Professor of Surgery and Chief Division of Transplantation, John S. Najarian Surgical Chair in Clinical Transplantation, Department of Surgery, University of Minnesota; Executive Medical Director, Solid Organ Transplant Service Line, M Health Fairview

Session Title: Novel immunosuppression

Session Date and Time: Tuesday, September 22, 2026, from 8:00AM to 9:00AM AEST

Session Room: Room C4.9

Presentation Time: 8:00AM AEST

About Eledon Pharmaceuticals and tegoprubart

Eledon Pharmaceuticals, Inc. is a clinical stage biotechnology company that is developing immune-modulating therapies for the management and treatment of life-threatening conditions. The Company’s lead investigational product is tegoprubart, an anti-CD40L antibody with high affinity for the CD40 Ligand, a well-validated biological target that has broad therapeutic potential. The central role of CD40L signaling in both adaptive and innate immune cell activation and function positions it as an attractive target for non-lymphocyte depleting, immunomodulatory therapeutic intervention. The Company is building upon a deep historical knowledge of anti-CD40L biology to conduct preclinical and clinical studies in kidney allograft transplantation, xenotransplantation, islet cell transplantation, liver transplantation and amyotrophic lateral sclerosis (ALS). Eledon is headquartered in Irvine, California. For more information, please visit the Company’s website at www.eledon.com.

Follow Eledon Pharmaceuticals on social media: LinkedIn; X

Investor Contact:

Stephen Jasper
Gilmartin Group
(858) 525 2047
[email protected]

Media Contact:

Jenna Urban
CG Life
(212) 253 8881
[email protected]


Risks

  • Phase 2 clinical data may still require further validation in larger Phase 3 trials before regulatory approval and commercial availability, posing execution risk.
  • Immunosuppressive drug development carries risks of adverse effects or insufficient efficacy, which could impact future trial outcomes.
  • Market adoption and competitive landscape for transplant immunosuppressants remain uncertain, potentially limiting commercial success.

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