Insider Trading March 31, 2026

Rapport Therapeutics COO Disposes of $281,857 in Stock; Company Advances RAP-219 Program

Cheryl Gault sold 10,000 shares under a 10b5-1 plan as Rapport prepares earlier-than-expected Phase 3 starts for RAP-219

By Maya Rios RAPP
Rapport Therapeutics COO Disposes of $281,857 in Stock; Company Advances RAP-219 Program
RAPP

Rapport Therapeutics Chief Operating Officer Cheryl Gault sold 10,000 shares of the company's common stock on March 30, 2026, in two transactions totaling $281,857 under a Rule 10b5-1 trading plan. The company recently reported fiscal 2025 results and Phase IIa data for RAP-219 in focal seizures, and plans to begin two Phase 3 studies in the second quarter of 2026 following an end-of-phase-2 meeting with the FDA in December 2025. Analysts have maintained Buy ratings with price targets across a wide range.

Key Points

  • COO Cheryl Gault sold 10,000 Rapport Therapeutics shares on March 30, 2026, for $281,857 under a Rule 10b5-1 plan.
  • Rapport reported fiscal 2025 results and Phase IIa data for RAP-219 in focal seizures, and intends to start two Phase 3 FOS studies in Q2 2026 after an FDA end-of-phase-2 meeting in December 2025.
  • Analysts have maintained Buy ratings with price targets ranging from $40 to $80, and specific targets from Truist ($44), Stifel ($56), Jones Trading ($50), and BTIG ($53 after a raise).

Transaction details

Cheryl Gault, Chief Operating Officer of Rapport Therapeutics, Inc. (NASDAQ:RAPP), executed a sale of 10,000 shares of common stock on March 30, 2026, as reported on a Form 4 filed with the Securities and Exchange Commission. The disposition comprised two separate trades totaling $281,857.

The first trade sold 7,161 shares at a weighted average price of $28.0401, with execution prices spanning $27.42 to $28.41. The second trade sold 2,839 shares at a weighted average price of $28.5530, with execution prices ranging from $28.42 to $28.72. Following these sales, Gault directly holds 159,914 shares of Rapport Therapeutics.

The transactions were carried out under a pre-arranged Rule 10b5-1 trading plan that was adopted on December 10, 2025.


Stock performance and valuation notes

RAPP shares have advanced 176% over the past year and are currently trading at $31.29. An InvestingPro analysis cited in the filing indicates the stock appears overvalued relative to its Fair Value, though analysts remain largely positive with price targets reported in the range from $40 to $80. The InvestingPro note also references the availability of eight additional exclusive tips and comprehensive financial metrics for investors.


Clinical program and company updates

Rapport Therapeutics released fiscal year 2025 results contemporaneously with the release of Phase IIa clinical data for RAP-219 in focal seizures. Management said the company plans to initiate two Phase 3 studies of RAP-219 in focal onset seizures in the second quarter of 2026, which the company describes as earlier than initially expected. This schedule follows an end-of-phase-2 meeting with the FDA in December 2025.

The company is progressing its Phase 3 focal onset seizure (FOS) program and is exploring additional development opportunities in primary generalized tonic-clonic seizures (PGTCS) and bipolar mania.


Analyst coverage

Several sell-side firms have reiterated their Buy ratings on Rapport Therapeutics. Truist Securities, Stifel, and Jones Trading each reaffirmed Buy ratings with price targets of $44, $56, and $50, respectively. BTIG also maintained a Buy rating and raised its price target from $47 to $53, citing progress in trial phases and opportunities for indication expansion. BTIG additionally noted that, despite impressive azetukalner results, there were no direct implications for Rapport Therapeutics from the X-TOLE2 readout.


Context and limitations

The insider sale was executed under a pre-established trading arrangement and took place while the stock has experienced a significant run-up. Investors and observers should note the company’s stated plans for Phase 3 initiation and the range of analyst price targets, as well as the InvestingPro valuation assessment indicating the shares appear overvalued relative to Fair Value.

Risks

  • Clinical development risk - The company's near-term plans to initiate Phase 3 studies mean clinical outcomes will materially affect the biotech sector and RAPP market performance.
  • Valuation uncertainty - InvestingPro analysis indicates RAPP appears overvalued relative to its Fair Value, which presents market risk for equity investors in the healthcare and biotech sectors.
  • Regulatory and timing uncertainties - While the company reported an end-of-phase-2 meeting with the FDA in December 2025 and plans earlier Phase 3 starts, the regulatory process and trial timelines remain potential sources of uncertainty for investors.

More from Insider Trading

Platinum Equity Disposes of 1.35M Ingram Micro Shares in $28.8M Trade Mar 31, 2026 Adaptive Biotechnologies President Disposes of $751k in Stock While Exercising Options Mar 31, 2026 Palladyne AI CFO Sells Small Block of Stock to Cover RSU Taxes; Company Posts Strong Revenue Gain but Remains Unprofitable Mar 31, 2026 Palladyne AI Chief Legal Officer Sells $19,251 in Stock to Cover RSU Taxes Mar 31, 2026 Palladyne AI CTO Sells $84,020 in Stock to Cover RSU Taxes Mar 31, 2026