Insider Trading January 28, 2026

Harmony Biosciences CFO Disposes $139K in Stock Amid Strong WAKIX Sales and Clinical Updates

Sandip Kapadia sold 3,746 shares under a 10b5-1 plan as the company reports robust 2025 WAKIX revenue and early positive Phase 3 clinical data

By Avery Klein HRMY
Harmony Biosciences CFO Disposes $139K in Stock Amid Strong WAKIX Sales and Clinical Updates
HRMY

Harmony Biosciences Holdings' Chief Financial Officer, Sandip Kapadia, sold 3,746 shares on January 26, 2026, for $139,171 under a Rule 10b5-1 trading plan. The company reported preliminary unaudited WAKIX net product revenue of roughly $243 million for Q4 2025 and $868 million for the full year, a 21% increase versus 2024, and issued a 2026 WAKIX revenue projection between $1.0 billion and $1.04 billion. Harmony also disclosed collaborations and initial Phase 3 clinical trial results for EPX-100 in Dravet syndrome, and a Buy reiteration from H.C. Wainwright with a $55 target.

Key Points

  • Harmony CFO Sandip Kapadia sold 3,746 shares on January 26, 2026, for $139,171 via a Rule 10b5-1 plan; he retains 24,521 shares.
  • Preliminary unaudited WAKIX net product revenue was about $243 million in Q4 2025 and $868 million for the full year, up 21% year-over-year.
  • Harmony forecasted 2026 WAKIX revenue of $1.0 billion to $1.04 billion; the company announced clinical collaborations and positive initial Phase 3 ARGUS results for EPX-100, and received a Buy reiteration with a $55 target.

Harmony Biosciences Holdings (NASDAQ: HRMY) confirmed that Chief Financial Officer Sandip Kapadia sold 3,746 shares of the company’s common stock on January 26, 2026, receiving a total of $139,171. The sales were carried out through a Rule 10b5-1 trading plan and executed at a weighted average price of $37.152 per share, with individual transactions ranging from $36.57 to $37.70.

After the disposition, Kapadia holds 24,521 shares directly in Harmony Biosciences. The company is currently valued at approximately $2.13 billion and is identified as having an "EXCELLENT" financial health score in external analytics referenced in company materials.

Market metrics highlighted by analysts show a trailing price-to-earnings ratio of 11.66 for the stock, which has been characterized as low relative to near-term earnings growth. Industry consensus among analysts is described as leaning bullish, and Harmony’s next scheduled earnings announcement is set for March 3.


Commercial performance and guidance

Harmony provided preliminary unaudited net product revenue figures for its lead product, WAKIX. The company reported approximately $243 million in WAKIX net product revenue for the fourth quarter of 2025 and about $868 million for the full year. Those figures represent year-over-year growth of 21% versus 2024.

Looking forward, Harmony projected 2026 WAKIX revenue in a range between $1.0 billion and $1.04 billion, a level the company said could place the product into blockbuster territory should the guidance be realized.


Clinical and strategic developments

On the clinical front, Harmony announced a collaboration with Beacon Biosignals to incorporate quantitative EEG measurements into two Phase 3 studies of HBS-301, which is being evaluated for narcolepsy and idiopathic hypersomnia.

The company also disclosed initial results from the Phase 3 ARGUS trial of EPX-100 for Dravet syndrome. Harmony said the preliminary data showed a median reduction in motor seizure frequency of approximately 50% among trial participants. These findings were presented at the American Epilepsy Society Annual Meeting.

Following the ARGUS data release, H.C. Wainwright reiterated a Buy rating on Harmony Biosciences and maintained a $55.00 price target.


Investor resources and next steps

For investors seeking additional analysis, the company’s coverage is available in extended research reports that encompass HRMY and a broad set of U.S. equities. The next earnings report on March 3 will provide updated financials and could inform near-term market reactions.

Risks

  • Upcoming earnings report on March 3 could materially change near-term financial expectations for investors.
  • The 2026 WAKIX revenue range is guidance and not guaranteed; actual sales may differ from the projected $1.0 billion to $1.04 billion figure.
  • The ARGUS results reported are initial Phase 3 data; subsequent data or analyses could alter the trial’s overall interpretation.

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