Insider Trading January 23, 2026

CareDx CEO Executes Share Sale Amid Strong Revenue Growth and Strategic Advances

John Walter Hanna Jr. reduces stake via Rule 10b5-1 plan as CareDx posts notable Q4 and full-year 2025 revenue gains

By Nina Shah CDNA
CareDx CEO Executes Share Sale Amid Strong Revenue Growth and Strategic Advances
CDNA

John Walter Hanna Jr., President and CEO of CareDx, Inc., sold 19,480 shares of company stock through pre-arranged trades in January 2026, totaling $412,222. The sales occurred across two days with prices ranging from $21.00 to $21.43 per share. Despite this decrease, Hanna maintains direct ownership of over 597,000 shares. CareDx reported strong financial performance in late 2025, including a 25% increase in Q4 revenue to $108 million and expects a 14% revenue rise for the full year 2025. Strategic initiatives include a partnership with 10x Genomics to enhance transplant organ rejection research. However, the company’s stock rating was recently downgraded from Buy to Hold by Craig-Hallum, reflecting cautious outlooks on risk and rewards.

Key Points

  • CEO John Walter Hanna Jr. executed sales of 19,480 CareDx shares totaling $412,222 under a Rule 10b5-1 plan.
  • CareDx posted 25% revenue growth in Q4 2025 to $108 million and expects full-year 2025 revenue to increase 14% to $380 million.
  • Strategic collaboration with 10x Genomics aims to enhance research on transplant organ rejection through the ImmuneScape initiative.

John Walter Hanna Jr., who serves as President and Chief Executive Officer at CareDx, Inc. (NASDAQ: CDNA), executed the sale of 19,480 shares of common stock on January 21 and 22, 2026, as detailed in a recent Securities and Exchange Commission filing. These dispositions yielded total gross proceeds of approximately $412,222.

The transactions were carried out at varying prices over two consecutive trading days. On January 21, Hanna sold 200 shares at a fixed price of $21 per share. Subsequent sales on January 22 involved multiple transactions summing to 19,280 shares, with prices fluctuating between $21.00 and $21.43 per share.

Following these transactions, Hanna continues to hold a substantial equity interest in CareDx, directly owning 597,405 shares. The share sales were executed under a Rule 10b5-1 trading plan which Hanna adopted on December 13, 2024, allowing for scheduled transactions irrespective of nonpublic information.

In parallel with these insider sales, CareDx disclosed a favorable financial performance for the fourth quarter of 2025, reporting revenue of roughly $108 million, marking a 25% increase compared with the prior year’s period. Furthermore, the company projects full-year 2025 revenues to reach near $380 million, translating to an approximate 14% annual growth rate.

CareDx’s core testing services business contributed significantly to this growth, generating about $78 million in revenue during the fourth quarter, up 23% year-over-year. The company additionally announced a collaborative venture with 10x Genomics, establishing a new research initiative named ImmuneScape. This partnership aims to employ advanced technological platforms to investigate mechanisms of transplant organ rejection at a cellular level.

On the market perception front, Craig-Hallum has recently downgraded CareDx’s shares from a Buy to a Hold rating, citing a less attractive risk-reward outlook. Despite this, CareDx has released data indicating its HeartCare molecular testing platform’s capability to help identify heart transplant recipients at a higher risk of developing complications.

Moreover, CareDx surpassed revenue estimates in the third quarter of 2025, reporting $100.1 million against the anticipated $95.32 million, with earnings per share that considerably exceeded analysts’ expectations.

Risks

  • Recent downgrade of CareDx stock by Craig-Hallum from Buy to Hold reflects uncertainties in the risk-reward profile affecting investor sentiment.
  • Insider sales, while pre-arranged, may prompt market scrutiny regarding executive confidence levels in stock valuation.
  • Market reliance on growth in testing services and new initiatives may be impacted by industry competition and advances, potentially affecting future revenue prospects.

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