Insider Trading March 9, 2026

Altimmune CEO Purchases $70,790 in Stock Amid Weak Q4 Results

Jerome Durso buys 20,000 shares as company reports earnings and revenue shortfalls and faces a competitive therapeutic landscape

By Priya Menon ALT
Altimmune CEO Purchases $70,790 in Stock Amid Weak Q4 Results
ALT

Altimmune President and CEO Jerome Benedict Durso acquired 20,000 shares of the company on March 6, 2026, paying a weighted average of $3.5395 per share for a total of $70,790. The purchase occurred while the stock traded near $3.54 after a 15% decline over the prior week. The company recently reported fourth-quarter 2025 results that missed expectations on both EPS and revenue, and analysts reiterated a Market Perform rating following Phase IIb trial results that showed activity but limited clinical differentiation.

Key Points

  • CEO Jerome Benedict Durso purchased 20,000 Altimmune shares on March 6, 2026 at a weighted average price of $3.5395, totaling $70,790.
  • Altimmune reported Q4 2025 EPS of -$0.27 and revenue of $26 million, both falling short of analyst expectations.
  • William Blair kept a Market Perform rating after the Phase IIb IMPACT trial showed activity for pemvidutide but lacked clear clinical differentiation in a competitive therapeutic market.

Altimmune, Inc. (NASDAQ: ALT) disclosed a direct purchase of company common stock by President and Chief Executive Officer Jerome Benedict Durso on March 6, 2026, according to a Form 4 filing with the Securities and Exchange Commission.

The filing shows Durso bought 20,000 shares at a weighted average price of $3.5395, with per-share prices in the transaction ranging from $3.5300 to $3.5500. The aggregate cost of the acquisition was $70,790. At the time of the transaction, the stock had slipped roughly 15 percent over the previous week and was trading near $3.54.

Following the purchase, Durso's direct holdings in Altimmune stand at 32,500 shares. Separately, analysis from InvestingPro indicates the stock appears to be trading above its Fair Value benchmark.


Financial results announced for the fourth quarter of 2025 showed Altimmune reporting an earnings per share (EPS) loss of $0.27, missing the forecasted loss of $0.25 and constituting an EPS surprise of -8 percent. Revenue for the quarter reached $26 million, which was substantially below the expected $625 million stated in the report.

Following the quarterly announcement and the interim data from Altimmune's Phase IIb IMPACT trial of pemvidutide in MASH, William Blair maintained a Market Perform rating on the stock. The trial demonstrated therapeutic activity but, according to the firm, did not provide clear clinical differentiation in a competitive market that includes treatments from Madrigal, Novo Nordisk, Boehringer Ingelheim, and Eli Lilly.


The purchase by the chief executive comes amid pronounced investor scrutiny after the earnings and revenue misses and ongoing competitive pressures in the metabolic and liver disease treatment space. The filing and the contemporaneous valuation assessment by InvestingPro are part of the recent developments surrounding Altimmune.

Readers interested in additional proprietary valuation context can access comprehensive Pro Research Reports that cover ALT alongside more than 1,400 U.S. equities, which the service promotes as offering in-depth analysis for investment decision-making.


Given the details in the filings and the company disclosures, market participants will likely note both the insider purchase and the recent operating results as part of their ongoing assessment of Altimmune's prospects.

Risks

  • Reported fourth-quarter EPS and revenue missed forecasts, highlighting near-term financial and execution risk for the company; this impacts the biotech and healthcare sectors and equity market valuations.
  • Phase IIb trial results for pemvidutide showed therapeutic activity but no clear clinical differentiation, introducing clinical-development and competitive risk within the pharmaceutical and biotech markets.
  • External valuation analysis indicates the stock may be overvalued relative to Fair Value, creating valuation and investor-sentiment risk for equity investors.

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