VXRT May 8, 2026

Vaxart Q1 2026 Earnings Call - Sentinel Cohort Data Delayed, Revenue Doubles, Runway Extended to Q2 2027

Summary

Vaxart reported a strong first quarter with revenue doubling to $39.2 million, driven by BARDA contracts and Dynavax licensing, resulting in a rare net profit of $5.2 million for a clinical-stage biotech. The company extended its cash runway into Q2 2027 through cost discipline and a new $25 million share purchase agreement with Lincoln Park Capital. However, the market’s focus remains on the delayed release of the 400-person sentinel cohort data from its BARDA-funded Phase II-B COVID-19 trial. Management attributed the delay to standard, albeit slower-than-anticipated, administrative and data-validation protocols with its government partner, while emphasizing that the cohort was never designed to power a statistically significant efficacy comparison against mRNA vaccines. Definitive efficacy data is still expected from the main 5,000-participant cohort in early 2027.

Beyond the immediate clinical catalyst, Vaxart is actively seeking external funding or a partnership to advance its norovirus program, with CEO Steven Lo stressing that the company will not rush into an underpowered trial. The board was refreshed with the addition of Dr. James Breitmeyer, a veteran drug developer, to oversee the upcoming regulatory pathways. Sanofi, having acquired Dynavax, maintains an exclusive worldwide license option for the COVID-19 program, contingent on the Phase II-B results. Meanwhile, the company faces ongoing scrutiny from shareholders regarding Nasdaq compliance and board governance, though management remains focused on executing its clinical strategy as the primary driver of long-term value.

Key Takeaways

  • Revenue doubled to $39.2 million in Q1 2026, up from $20.9 million in Q1 2025, primarily driven by BARDA contract growth and Dynavax licensing revenue.
  • Vaxart posted a net income of $5.2 million ($0.02 per share), a rare profitability milestone for a clinical-stage biotech, aided by reduced R&D and G&A expenses.
  • Cash and short-term investments stood at $61 million, with the company extending its cash runway into Q2 2027 through cost-cutting and operational streamlining.
  • A $25 million share purchase agreement was established with Lincoln Park Capital, providing discretionary, non-dilutive capital access over the next 24 months.
  • The release of the 400-person sentinel cohort data from the Phase II-B COVID-19 trial has been delayed beyond Q2 due to slower-than-expected administrative and data-validation protocols with BARDA.
  • Management stressed that the sentinel cohort was never powered to provide a statistically significant efficacy comparison against mRNA vaccines, focusing instead on safety, immunogenicity, and mucosal immune response.
  • Definitive efficacy and safety data from the fully powered 5,000-participant main cohort is now expected in early 2027.
  • The norovirus program remains contingent on securing external funding or a partnership; CEO Steven Lo emphasized the company will not rush into an underpowered trial.
  • BARDA’s support is currently focused solely on the COVID-19 program, with no announced additional funding for norovirus or flu candidates at this time.
  • Sanofi, having completed its acquisition of Dynavax, maintains an exclusive worldwide license option for the COVID-19 program, which can only be exercised after Phase II-B results and FDA meetings.
  • Veteran drug developer Dr. James Breitmeyer joined the board, bringing over 35 years of experience and leading multiple FDA-approved programs to strengthen clinical and regulatory oversight.
  • The company is actively engaging with potential partners for the norovirus program and continues to maintain dialogue with Sanofi regarding the broader collaboration.
  • Management faces ongoing shareholder scrutiny regarding Nasdaq compliance and board governance, with the proxy filing deadline for director nominations having closed in March 2026.
  • The company is refining its second-generation norovirus constructs against the prevalent GII.17 strain, with preclinical data expected later this year and a potential clinical trial initiation in 2026.
  • Vaxart completed a headquarters consolidation in April, significantly reducing long-term liabilities and fixed overhead to focus capital on core clinical catalysts.

Full Transcript

Operator: Greetings and welcome to the Vaxart Stockholder Fireside Chat Conference Call. A question and answer session will follow management’s opening remarks. Individual investors may submit written questions via the webcast portal. As a reminder, this conference is being recorded. I would now like to turn the webcast over to David Carey of Finn Partners.

David Carey, Moderator, Finn Partners: Thank you, operator. Good afternoon, and welcome to today’s call. Joining us from Vaxart are Steven Lo, Chief Executive Officer, Dr. Sean Tucker, Founder and Chief Scientific Officer, Dr. James Cummings, Chief Medical Officer, Jeroen Grasman, Chief Financial Officer, and Ed Berg, Senior Vice President and General Counsel. Before we begin, I would like to remind everyone that during this conference call, Vaxart may make forward-looking statements, including statements about the company’s financial results, financial guidance, its future business strategies and operations, any partnerships with third parties, timing of any anticipated regulatory approvals or that any such approvals will be obtained, the company’s future cash runway, ability to regain compliance with Nasdaq listing standards or raise capital if such listing is regained, and its product development and regulatory process, including statements about its ongoing or planned clinical trials.

Actual results could materially differ from those discussed in these forward-looking statements due to a number of important factors, including uncertainty inherent in the clinical development and regulatory process and other risks described in the Risk Factors section of Vaxart’s most recently filed annual report on Form 10-K and also in other public periodic reports filed with the SEC. Vaxart undertakes no obligation to update any forward-looking statements after the date of this call. I’ll now turn the call over to Steven Lo. Steve?

Steven Lo, Chief Executive Officer, Vaxart: Thanks, David. Good afternoon, everyone, and thank you for joining us. In the first quarter, we made meaningful progress advancing our clinical programs and preparing for key data milestones that we believe will help demonstrate the value of our oral vaccine platform. Beyond preparing our COVID-19 program for its upcoming readout, we have also spent the last few months strengthening our financial position and streamlining our operations to support disciplined execution and extend our runway. Specifically, our work during the first quarter was focused on the steps needed to disclose data from the 400-person sentinel cohort of our phase II-B COVID-19 trial. This cohort is an important part of our program, providing our first 12-month look at the safety, select efficacy measures, and mucosal immune response of our oral vaccine candidate in a head-to-head study.

We are currently working through the data reconciliation process required to complete the analysis and move toward a top-line readout. This effort is backed by a strong commitment from our partners at BARDA. To further strengthen our board and add clinical and strategic oversight, we were pleased to welcome Dr. James Breitmeyer to our board of directors in April. Jim is a veteran of drug development who has successfully led multiple candidates through complex clinical and regulatory pathways. He brings more than 35 years of biopharmaceutical experience, including leadership of programs resulting in multiple FDA approvals and global regulatory successes. As part of our ongoing commitment to board refreshment, with the addition of Dr. Breitmeyer, we have added 2 new directors with significant drug and business development expertise over the past 2 years to strengthen the addition of fresh perspectives.

We believe that adding directors with these proven track records is a significant advantage as we approach our upcoming data catalysts. On the operational side, we completed our headquarters move in April, consolidating and reducing our footprint, also established a $25 million share purchase agreement with Lincoln Park Capital. No shares have been sold to date, the use of this purchase agreement is subject to the company’s discretion. These steps are part of our ongoing effort to maintain a lean operation, provide financial flexibility, and position us to direct our capital toward our core drug development programs. We continue to maintain a productive dialogue with the team at Sanofi as we advance our COVID-19 program. I’ll turn the call over to James now to update you on where we stand with the COVID-19 trial. James?

Dr. James Cummings, Chief Medical Officer, Vaxart: Thanks, Steve. The primary goal of our phase II-B COVID-19 trial is to evaluate the safety and the efficacy of our oral vaccine pill against the leading injectable mRNA vaccines. This is the first time our mucosal technology has been clinically tested in a head-to-head comparison against an approved mRNA standard, which it’s a significant milestone for our platform. This first look at this head-to-head evaluation comes from our 400 person sentinel cohort. We are currently in the final administrative stage of data validation and quality reconciliation for this group. I want to be very direct on our current status. Vaxart management is currently blinded to the results and has not reviewed the data.

This is a standard procedure to ensure that the analyses are finalized before the results are unblinded and shared in accordance with our agreed-upon process with BARDA, our funder.Because this is a BARDA-funded study, there are established partnership protocols and data-sharing processes that govern the process of our unblinding. These are deliberate, and they are standard administrative steps required when working with a government partner. We are currently completing those final steps in coordination with BARDA to support the release of top-line results. As a reminder, the primary purpose of this Sentinel cohort is to evaluate the safety and the immunogenicity, including longer-term follow-up. While there will be some efficacy-related measures reported, this 400-person Sentinel cohort was not powered to provide statistically significant comparison between the oral pill and mRNA vaccine groups.

As we announced in January of 2025, an independent Data Safety Monitoring Board, or DSMB, has already conducted a planned review of the initial safety data from this cohort and recommended the study continue without any modifications. This provided an important external validation of our platform safety while we at Vaxart remain blinded to the full 12-month data. While these results are an important precursor to how our oral pill vaccine performs against mRNA vaccines, as we mentioned, this cohort was not powered to provide definitive efficacy comparison. More definitive insights are expected to come from our main cohort of approximately 5,000 participants, which is designed and powered to evaluate relative efficacy and safety. I’ll now turn the call over to Sean Tucker to discuss norovirus. Sean?

Dr. Sean Tucker, Founder and Chief Scientific Officer, Vaxart: Thank you, James. We are currently evaluating how our second-generation constructs perform against the GII.17 norovirus strain. GII.17 has become a much more prevalent strain, and we are testing our bivalent vaccine’s cross-neutralization capabilities to ensure it can recognize and neutralize this emerging variant. We expect to share that preclinical data and ad hoc clinical evaluations in the last study later this year in both scientific meetings and potentially scientific publications. Regarding the next steps for norovirus, we are prepared to initiate our next clinical trial in 2026, depending on a partnership or the receipt of other funding. In the meantime, we are continuing to refine our VAAST platform and our manufacturing processes in order to ensure our high-yield tableting is ready for large-scale needs. I’ll now hand the call over to Jerome for the financials. Jerome?

Jeroen Grasman, Chief Financial Officer, Vaxart: Thank you, Sean. Vaxart ended the first quarter with cash equivalents, and short-term investments of $61 million. Revenue for the first quarter was $39.2 million compared to $20.9 million last year, with the growth in revenue primarily driven by our BARDA contract. First quarter 2026 also included revenue recognized from the Dynavax license and collaboration agreement signed in November 2025. We also reduced our R&D and G&A expenses compared to the first quarter of 2025 by closely managing personnel and facilities costs. The revenue growth and cost control measures led to a net income of $5.2 million for the quarter, or $0.02 per share. As Steve mentioned, we enhanced our financial flexibility in April by establishing a $25 million share purchase agreement with Lincoln Park Capital.

This facility provides us with an efficient capital management tool that we can utilize to support our capital needs at our discretion over the next 24 months. Based on our current plan, we continue to expect our cash runway to extend into the second quarter of 2027. With the headquarters move completed and the lease termination taking effect next week, we have significantly reduced our long-term liabilities and fixed overhead, allowing us to focus our resources on our clinical catalysts. We’ll now take your questions.

David Carey, Moderator, Finn Partners: Thanks, Jeroen.

Jeroen Grasman, Chief Financial Officer, Vaxart: David?

David Carey, Moderator, Finn Partners: Yep, thank you. We’ve received numerous questions from many shareholders, there were several overlaps. We’re grouping the questions initially together by topic. The first question is we’ve been getting a lot of questions, the primary focus of the Sentinel readout, and if it is safety and not efficacy. In addition, the questions regarding whether people can expect the readout given that early Q2 has already passed. I’ll turn that question to James. James?

Dr. James Cummings, Chief Medical Officer, Vaxart: Sorry, I was stuck on mute. Thanks, David. You know, as a reminder that the primary purpose of this Sentinel cohort is to evaluate safety and immunogenicity, including longer-term follow-up. It is not, and it’s never been the purpose to evaluate efficacy. While there will be some efficacy-related measures reported, this 400-person Sentinel cohort wasn’t powered to provide, this is the important part, a statistically significant comparison between the oral pill and mRNA vaccine groups. As we announced in January 2025, an independent Data Safety Monitoring Board already conducted a planned review of the initial safety data from this cohort, and it recommended the study continue without any modifications. The DSMB has continued to meet and reaffirm these findings. This provides important external validation of our platform safety while we remain blinded to the full 12-month data.

While these results are an important precursor to know how our oral pill vaccine performs against mRNA vaccines, you know, as I mentioned, this cohort was not powered to provide a definitive efficacy comparison, this smaller cohort. That’s because it’s a 400-person cohort and would not be specifically powered to reach that conclusion. This ensures enough data is collected to avoid false negatives, ensuring results are not due to chance. More definitive insights are expected to come from our main cohort of the approximately 5,000 participants in this study, and it’s designed and powered to evaluate relative efficacy and safety. In addition, we’re dedicating significant resources to manage the 5,000 participant main study cohort, which is a primary focus of our clinical efforts. We anticipate the primary efficacy and safety data readout from this larger group in early 2027.

I think that sums it up, David.

David Carey, Moderator, Finn Partners: Okay. Thank you, James. Next question is also for you. Does Vaxart believe there will be a meaningful difference in immunogenicity, longevity, and cross-reactivity of immune response and viral load reduction that would be visible even in a small cohort?

Dr. James Cummings, Chief Medical Officer, Vaxart: Thanks, David. You know, I’m not gonna jump to any conclusions or predetermine any outcomes here. We’re blinded to the data. Once we’re unblinded, we will evaluate it for appropriate context.

David Carey, Moderator, Finn Partners: Thanks, James. Another question for you. What specifically still needs to be done by Vaxart and BARDA in order to release the sentinel cohort data?

Dr. James Cummings, Chief Medical Officer, Vaxart: You know, as I mentioned earlier, we’re currently in the final administrative stage of data validation and quality reconciliation from this group, and that’s pretty standard. As part of this process, the data is being carefully reviewed to ensure accuracy, completeness, consistency prior to analysis. Again, typical for a study of this size and importance. This means that a third party is evaluating the database to ensure the data has been entered correctly and to identify any records that might be incomplete. This is done to ensure that the final analysis is done on the most accurate data possible. We’re working closely with our partners at BARDA to complete these steps in order to release the sentinel cohort data. To be clear, though, you know, this is a procedural matter. It is not a data issue. The study remains blinded, and we have not yet seen the results ourselves.

David Carey, Moderator, Finn Partners: Thanks, James. Next question we’ve received from several individuals and also on the online portal here this afternoon. Why has the timeline slipped? Are you confident that the data will be released before the end of the quarter?

Dr. James Cummings, Chief Medical Officer, Vaxart: That’s a fair question. You know, the third-party review is taking a little longer than anticipated because there are some very specific partnership protocols and some contractual data-sharing guidelines that govern the timing of our unblinding. These are deliberate administrative steps required when you work with a contractual partner. All this is taking really a lot more time than we’d hoped. We are working through those final steps now. While we are still aiming to release the top-line results in Q2, it’s important to remember that we are working with a contractual partner, and we’re not in full control of that timing. That’s my projection.

David Carey, Moderator, Finn Partners: Okay. James, can you provide additional details as to what BARDA is requesting from Vaxart that’s causing the delay in disclosing your safety data?

Dr. James Cummings, Chief Medical Officer, Vaxart: Sure. As part of our collaboration, BARDA is working with us to finalize the analysis plan and ensure all relevant data elements are incorporated for the Sentinel cohort, you know, something I mentioned previously. This includes reviewing certain information that’s typically addressed later in the study, but it’s being incorporated at this stage to support a thorough and aligned analysis process. We continue to work closely together to complete these steps and ensure the data are fully validated and ready for disclosure.

David Carey, Moderator, Finn Partners: Thanks, James. Next question. Does the delay in reporting the results from the sentinel cohort indicate that there is a problem with the data or the process for collecting or analyzing it?

Dr. James Cummings, Chief Medical Officer, Vaxart: It’s starting to sound like the James show. No, it does not. This is part of BARDA’s regular process for data analysis and sharing. It is not related to the data, the collection process, or the analyses. Our government partner has specific protocols governing when and how blinded data can be unblinded and shared. Those steps have taken longer than we originally anticipated, but they are procedural in nature. Vaxart management is currently blinded to the results, and we have not seen the data. Once we get the administrative clearance, we will flip the cards over, unblind, and report. Believe me, we’re excited to do so as you are.

David Carey, Moderator, Finn Partners: Okay. Thank you, James. Let’s switch to norovirus. Next question is, have there been any further conversations with your prospective partners about the norovirus program? Do you believe there’s a realistic chance of securing a funding partner before the end of the year for norovirus? Steve, I’ll turn that to you.

Steven Lo, Chief Executive Officer, Vaxart: Yes, we continue to have active discussions with potential partners, and I wanna just tell everybody this remains a priority for us. As you would expect, however, we can’t guarantee that there will be an agreement and when one may occur. I wanna assure everybody that, you know, we’re working continuously to make sure that we keep having good active discussions. This is with great focus and conviction on our team. You know, frankly, securing funding for this trial is a critical next step for the company, and we’re certainly treating it that way.

David Carey, Moderator, Finn Partners: Okay. Thank you, Steve. Next question is, what is the likelihood that a phase II-B norovirus trial begins in Q3? Steve, could you take that one?

Steven Lo, Chief Executive Officer, Vaxart: Yes. We understand, you know, this question’s about pace and let me take a few moments to explain how we approach this, right. The gating factor is funding. It’s not science. You know, we have noted that, and you’ve probably seen that, you know, advancing the norovirus program is important to us for the next clinical stage. That really is dependent on securing a partnership or some external funding. We are, like I said earlier, engaging with potential partners. We’re looking at various options, and we do wanna move this forward in a very strategic and capital efficient manner. Funding this does require significant resources, so it’s important that we align this program with the right partner, with the right funding structure to support its success.

Because we wanna be good stewards of shareholder capital, we’re not going to rush into a trial that’s gonna be underpowered or underdesigned just to hit a certain milestone.

David Carey, Moderator, Finn Partners: Thanks, Steve. Next question. Sean, could you please take this one? Has BARDA shown any interest in norovirus or flu? It would seem with their goal of next gen platforms that Vaxart is uniquely positioned to work with them to bring those products coming to market.

Dr. Sean Tucker, Founder and Chief Scientific Officer, Vaxart: Sure. Obviously, we have an ongoing and productive relationship with BARDA through our COVID-19 program, and of course, we had a past relationship with them on flu. They are really familiar with our platform and our broader capabilities. At this time, BARDA’s support is focused on the current COVID study, and we have not announced any additional funding from BARDA for the norovirus or flu programs. We will continue to evaluate a range of potential funding sources, including government and strategic partners, to advance all of our programs.

David Carey, Moderator, Finn Partners: Thanks, Sean. Do you believe you’ll be able to elicit VX-20 and or VX-22 antibodies in a majority of subjects before you begin the phase II? Sean, could you take that one?

Dr. Sean Tucker, Founder and Chief Scientific Officer, Vaxart: Yeah. It’s an interesting question. VX-20, VX-22 are monoclonal antibodies with broadly neutralizing capabilities and are cross-reactive against many different genotypes. Keep in mind, these antibodies were cloned from a Vaxart clinical trial participant. However, these clones may not be relevant for all people with various genetic backgrounds. Because of this, we are focused on efforts to advance our norovirus programs that can address all people and all genetic backgrounds. The key thing from this is that we are currently doing things that are much more proactive and relevant, but such as testing our bivalent vaccines cross-neutralizing capabilities against the GII.17 norovirus strain, which has recently become a more prevalent variant across the globe.

David Carey, Moderator, Finn Partners: Thanks, Sean. Next question. Can you give us an update on your interactions with Sanofi? Are you confident that Sanofi will continue the partnership that you established with Dynavax? Steve, could you take that please?

Steven Lo, Chief Executive Officer, Vaxart: Sure. As a reminder, Dynavax became a subsidiary of Sanofi, and that closed in the first quarter. Moving forward, I’ll generally refer to this collaboration as Sanofi. I’ll certainly let you all know that we continue to have and maintain a very good productive dialogue with the team at Sanofi as we advance the COVID-19 program forward. They share in our view that the global demand for COVID-19 vaccines remains robust. As a reminder to everybody, our exclusive license and collaboration agreement with Sanofi is a worldwide agreement. Sanofi has the option to assume full responsibility for the program only after evaluating the results from a phase IIb clinical trial and at the end of phase IIb meeting with the FDA.

Because this ongoing trial is heavily funded by BARDA, as we’ve discussed in the past, our partners at Sanofi certainly see this as gaining access to a high-value clinical data trial that has been significantly de-risked by government investment.

David Carey, Moderator, Finn Partners: Thanks, Steve. Next question. Has there been any update on the status of the avian influenza study, or when investors might expect to see the results? Sean, could you please take that?

Dr. Sean Tucker, Founder and Chief Scientific Officer, Vaxart: Yes. Again, our focus is on publishing this data in a peer-reviewed journal, and again, the timing is dependent on that process. As with other programs, we will certainly provide updates as appropriate and once that process is complete.

David Carey, Moderator, Finn Partners: Okay. Next question. What’s the rationale for doing a share purchase agreement at this time, given the company’s cash runway extends to the second quarter of 2027? Jeroen, could you please answer that?

Steven Lo, Chief Executive Officer, Vaxart: Sure. Thank you, David. This agreement enables us to strengthen our balance sheet

Jeroen Grasman, Chief Financial Officer, Vaxart: As needed and at our sole discretion. We’re able to do this at any point in time over the 24-month term of the agreement. We maintain full control over the timing and amount of any sales, as Lincoln Park is required to purchase the stock at our direction. This arrangement has the potential to also bring us broader benefits as a company as well. For example, a backstop financing facility can strengthen our hand in partnership negotiations because we have other access to capital. Also, as a high-value investment opportunity arises, we can act quickly without the time and expense of a traditional capital raise. Back to you, David.

David Carey, Moderator, Finn Partners: Thanks, Jeroen. Next question is also for you. Does Vaxart plan to use the additional capital for a specific purpose?

Jeroen Grasman, Chief Financial Officer, Vaxart: Sure. Yeah, first and foremost, as I just said, the share purchase agreement provides us with the financial flexibility and optionality at favorable terms versus a more traditional raise. Our disclosures have stated that the funds are intended to be used for working capital and general corporate purposes. The objective would clearly be here to support our existing priorities. That includes the advancement of our norovirus program, completing the ongoing clinical operations, and on other programs, and develop our pipeline, as we just talked about, avian flu programs and other vaccine candidates. In any case, use of proceeds would be to really fund activities that are value-creating and not merely to just extend our runway. David?

David Carey, Moderator, Finn Partners: Thanks, Jeroen. Next question is for Steve. Can you explain the rationale for bringing Dr. Breitmeyer onto the board at this time? Are there any more changes to the board planned?

Steven Lo, Chief Executive Officer, Vaxart: Dr. James Breitmeyer is a highly qualified pharmaceutical executive. He has experience being on boards. He has extensive clinical and regulatory experience spanning 35 years. You know, as we were approaching some of our very important critical data milestones, obviously including the upcoming readouts for our BARDA-funded COVID-19 program, Jim’s experience and his track record of leading programs to 8 FDA product approvals really provides us with a distinct advantage. Furthermore, on top of his previous work, he also served as president of Bavarian Nordic, which is a vaccine company, and there he oversaw the development of infectious disease and bioterrorism vaccines. It aligns perfectly with the work we’re doing alongside our government partners. That’s the reason why we believe that Jim’s expertise is really helping us navigate through this complex path from clinical development to regulatory approval.

It’ll be invaluable to us as we work through validating our oral vaccine platform.

David Carey, Moderator, Finn Partners: Okay. Steve, another question for you. Are any of Vaxart’s directors planning to step down, or are you expanding the board?

Steven Lo, Chief Executive Officer, Vaxart: We regularly evaluate board composition and current skill sets to ensure that we have the right expertise to support the company’s strategy and our stage of development. We believe that with the recent additions, the board, you know, does just that, right? As we demonstrated by the recent addition of Dr. Breitmeyer, our focus is strengthening capabilities in areas like clinical development and regulatory strategy. Also as part of our ongoing commitment to board refreshment, you know, with the addition of Dr. Breitmeyer, as a reminder, we’ve added two new directors in two years with significant drug and business development expertise, and that really ensures that we have fresh perspectives on the board.

David Carey, Moderator, Finn Partners: Okay. Thank you. A couple additional board questions. Next one, Steve. Can you clarify the rationale for recent board changes and how those decisions align with shareholder interests? Would you consider a retail shareholder representative to the board?

Steven Lo, Chief Executive Officer, Vaxart: The board believes it’s important to bring relevant fresh perspective to the boardroom regularly. Of course, these directors also need to provide rigorous oversight regarding the execution of our strategy. Their skills and experiences are critical in this regard. The recent board changes reflect a focus on ensuring that we do have the right mix of expertise to support the company’s current stage and its priorities. This also includes strengthening capabilities in areas like clinical development, regulatory strategy, capital markets. You know, those are important to a company like Vaxart as we advance our programs. These decisions are aligned with what the shareholder interests are by positioning the company to execute effectively and realize the maximum value of our platform and pipeline.

As we’ve shown, the board’s open to fresh perspectives and would consider and evaluate any qualified nominee as part of the board’s nominating and governance committee process.

David Carey, Moderator, Finn Partners: Okay. Next question. Why should shareholders have confidence in the current board and any new nominees to create value going forward? Steve?

Steven Lo, Chief Executive Officer, Vaxart: Yes. As I was saying earlier, our board is actively overseeing our strategy, how we allocate capital and the progress that we are making. They’re working closely with the leadership team and holding all of us accountable on the management team to deliver. In doing so, they’re putting the company in the best position possible to enhance shareholder value. As I stated earlier, right, we added 2 new directors, and they bring the right mix of medical, business, financial, and other relevant experience and experiences to and expertise to drive our company forward and also ensure that we have the cash runway to execute our strategy. Specifically, our board benefits from our directors’ broad mix of experiences across clinical development, regulatory strategy, commercialization, business development, amongst many areas, and that’s directly aligned with advancing our pipeline.

David Carey, Moderator, Finn Partners: Thanks. Steve, what do you think about the role shareholders should have in the selection of board of directors?

Steven Lo, Chief Executive Officer, Vaxart: Yeah. All shareholders, no matter how big or small, of their ownership stake, have a voice. Their vote matters as part of the annual meeting process. Our board of directors and management team are shareholders as well, and our interests are aligned with all Vaxart investors. Our shareholders should know that our directors are committed to creating value, taking action that are in the best interest of all Vaxart shareholders. They are overseeing a clear strategy to advance our programs, drive growth, and extend our runway, so ultimately we can create shareholder value.

David Carey, Moderator, Finn Partners: Okay. Thanks. Steve, another question for you. How will you build investor trust and drive shareholder value with urgency over the next year?

Steven Lo, Chief Executive Officer, Vaxart: Yes. Our top priority is delivering on the key clinical milestones, including the Sentinel readout, as we discussed, and the fully powered phase II-B data later this year. We believe those are the most important drivers of value. We’re focused on disciplined execution, cost management, as we explained earlier, ensuring resources are directed toward the highest impact programs while also maintaining our runway. Finally, our goal is to advance our clinical programs. As I stated earlier, generating meaningful data and leveraging those results to support partnership opportunities and the broader value of our platform.

David Carey, Moderator, Finn Partners: Okay. Thank you. Steve, next question. Do you believe near-term stock price appreciation is a priority? How are you thinking about that versus long-term, longer-term strategy?

Steven Lo, Chief Executive Officer, Vaxart: Yes, our board and management team are always focused on creating shareholder value for now and also for the future. We’re confident that these steps that we’re taking now to advance our pipeline while also extending our runway will create the most long-term value for shareholders. At the same time, we recognize that the importance of creating value in the near term and believe that we can do so through these same drivers that will deliver sustainable long-term value. It gets back to the science, delivering positive outcomes for patients, executing on our growth strategies, and achieving the strategic outcomes we’ve been talking about.

David Carey, Moderator, Finn Partners: Okay. Thank you. Jeroen, next question for you. There are questions on management balancing dilution risk with the needs to reserve flexibility. We also know people have asked when we would consider raising capital versus relying on partnership funding.

Jeroen Grasman, Chief Financial Officer, Vaxart: Thank you, David. I’d say our capital allocation strategy is really to balance the spending discipline with the advancement of our science and with the ultimate goal of positioning the company for stronger strategic and financial outcomes over time. In order to reach those outcomes, we need sufficient cash runway to execute the development of our vaccine portfolio over time. We’ve pursued and continue to pursue non-dilutive funding and partnerships, as demonstrated by the ongoing support from BARDA and our Dynavax collaboration, which both have provided meaningful validation and capital. Our most recent agreement with Lincoln Park Capital is another good example of our capital-raising strategy, and it’s intended to provide access to capital as needed rather than requiring us to raise funds in bulk all at once.

Finally, we’re also realistic that we need to raise cash in other ways in order to achieve the outcomes we’re seeking and ultimately maximize our shareholder value.

David Carey, Moderator, Finn Partners: Okay. Thank you, Jeroen. Thank you. Steve, next question is for you. What’s the plan and timeline for regaining compliance and relisting on Nasdaq? Would a reverse stock split be necessary in order to do so?

Steven Lo, Chief Executive Officer, Vaxart: You know, our focus is on executing our strategy and advancing our clinical programs, and we want to continue to focus on that. We believe that’s gonna be the primary driver of long-term value, and, you know, we do and continue to assess what’s the best approach based on market conditions and the company’s progress. We wanna really act in the best interest of the shareholders here. It’s really gonna be executing on our strategy and advancing our clinical programs.

David Carey, Moderator, Finn Partners: Okay. Thank you, Steve. The next group of questions is related to the proxy and the annual meeting. Ed, if you could take the first question. When do you plan to file your proxy statement?

Ed Berg, Senior Vice President and General Counsel, Vaxart: Sure. We will be updating our shareholders in due course with information about the annual meeting, and of course, that’ll come through our proxy filings. Like all public companies, we have a shareholders meeting every year, and shareholders will be hearing more about it in the future.

David Carey, Moderator, Finn Partners: Okay. Thank you. Ed, a few more questions for you related to this topic. Have you spoken to the concerned shareholder group?

Ed Berg, Senior Vice President and General Counsel, Vaxart: We do regularly engage with a broad range of shareholders, and we welcome dialogue and input from them, but we don’t comment on specific conversations. We remain committed to listening to shareholder perspectives, considering them in our regular course, and maintaining open lines of communication.

David Carey, Moderator, Finn Partners: Has the concerned shareholder group notified Vaxart that they intend to nominate candidates to the board? Have you received any nominees?

Ed Berg, Senior Vice President and General Counsel, Vaxart: We don’t comment on specific shareholder communications, like I said, or on potential actions. When we have disclosure obligations, we of course take those seriously. When there’s something to disclose, we’ll do so appropriately. Our slate of director nominees will be included in the proxy, which will be filed in the coming weeks.

David Carey, Moderator, Finn Partners: Okay, a follow-on question. When was the deadline for the concerned shareholders group to submit their proposal for directors?

Ed Berg, Senior Vice President and General Counsel, Vaxart: Our nomination window for directors was between February 2nd, 2026 and March 4th, 2026. That window has closed. Of course, I’ll tell everyone to stay tuned for our proxy filing.

David Carey, Moderator, Finn Partners: Okay. Thank you, Ed. Checking on the Q&A portal, it looks like all the questions that have been submitted have been covered, and we haven’t received any further questions. Steve, I’ll turn the call back over to you for closing remarks.

Steven Lo, Chief Executive Officer, Vaxart: Okay. Thanks, David. I want to thank you all for joining us today and submitting your questions. We appreciate how engaged all of our shareholders are. This is an exciting and important time for Vaxart. We are advancing our programs. We’re on the precipice of releasing data and taking prudent steps to extend our runway and ensure we have the flexibility and resources to execute on our current strategy. We remain committed to creating safe, effective, and accessible oral pill vaccines that protect our global communities and help people to lead healthier lives. In doing so, we are confident we can create sustainable shareholder value. Thank you again.