Pacira BioSciences Q1 2026 Earnings Call - EXPAREL Volume Surge and PCRX-201 Catalysts Drive 5x30 Momentum

Conference Call Operator: Good day, and thank you for standing by. Welcome to the Q1 2026 Pacira BioSciences, Inc. earnings conference call. At this time, all participants are in a listen-only mode. After the speaker’s presentation, there will be a question and answer session. Please be advised that today’s conference is being recorded. I would now like to hand the conference over to your first speaker today, Susan Mesco, Head of Investor Relations. Please go ahead.

Susan Mesco, Head of Investor Relations, Pacira BioSciences, Inc.: Thank you. Good afternoon, everyone. Welcome to today’s conference call to discuss our first quarter 2026 financial results. Joining me are Frank Lee, Chief Executive Officer, Brendan Teehan, Chief Commercial Officer, and Shawn Cross, Chief Financial Officer. Kristen Williams, Chief Administrative Officer and Secretary, Tony Malloy, Chief Legal Officer, and Jonathan Slonin, Chief Medical Officer, are also here for today’s question and answer session. Before we begin, let me remind you that this call will include forward-looking statements subject to the safe harbor provisions of federal securities laws. Such statements represent our judgment as of today and may involve risks and uncertainties. This may cause our actual results, performance, or achievements to differ materially. For information concerning risk factors that could affect the company, please refer to our filings with the SEC or the pacira website.

Lastly, as a reminder, we will be discussing non-GAAP financial measures on today’s call. A description of these metrics, along with our reconciliation to GAAP, can be found in the news release issued this afternoon. With that, I will now turn the call over to Frank Lee.

Frank Lee, Chief Executive Officer, Pacira BioSciences, Inc.: Thank you, Susan. Good afternoon to everyone joining today’s call. Just over a year ago, we introduced our 5x30 strategy. This plan was designed to accelerate performance and position the company for sustainable growth and shareholder value creation. To remind you, 5x30 was built to deliver measurable progress around five key goals: patients served, product revenue, profitability, pipeline, and partnerships. Collectively, we believe advancing these five goals will drive shareholder value into and well beyond 2030. Let me start by saying that I’m pleased with our first quarter results. I’d like to recognize our team for their remarkable efforts. Our solid first quarter results reinforce our confidence that 5x30 is delivering its intended business results, and we’re on the right strategic path. One year into execution, our progress across all five goals is clear.

This is reflected in our commercial performance, financial results, and pipeline advancements. I’ll start with our flagship product, EXPAREL. Since our founding, EXPAREL has been the cornerstone of Pacira’s leadership in opioid-sparing innovation for post-surgical pain. Through the dedicated efforts of our team, EXPAREL is demonstrating renewed growth more than a decade after its initial launch. This is a rarity in the pharmaceutical industry and a clear testament to the strength of our commercial, medical, and market access organizations. The accelerating volume growth we delivered in the second half of 2025 has continued into 2026. This momentum reflects a combination of fundamental improvements that are strengthening the long-term durability of our franchise, including expanding coverage outside the surgical bundle for Medicare patients following implementation of the NOPAIN Act at the beginning of 2025. A new product-specific J-code enabling streamlined billing and reimbursement.

Growing commercial payer coverage outside the surgical bundle, which Bren will discuss in more detail shortly. Increased awareness and adoption of non-opioid stewardship programs, as evidenced by encouraging market research results. Enhanced intellectual property protection, providing greater long-term visibility for the franchise. We now have 21 Orange Book-listed patents across 2 families protecting EXPAREL from generic challengers. This is a dramatic evolution from the single patent previously litigated and supported a favorable volume-limited settlement in 2025. This multi-year EXPAREL patent infringement litigation began in 2021 and extended through 2024. In addition to EXPAREL’s leadership in post-surgical pain control, Zilretta and iovera’s position in early intervention OA pain management are expanding. For Zilretta, the year is off to a strong start with a 15% year-over-year increase in sales. We believe the growth initiatives we put in place last year are now beginning to deliver results.

These include our dedicated Zilretta sales force, expanded patient access programs, and extended promotional reach through our Johnson & Johnson MedTech collaboration. From a lifecycle management perspective, we’re pleased to report enrollment has concluded for a phase III registrational study in shoulder OA. This places us on track for top-line results later this year. The unmet need for shoulder OA is significant. There are approximately 1 million injections for shoulder OA administered annually in the U.S. despite the absence of FDA-approved products. If this phase III trial meets its objectives, Zilretta could become the first product with a labeled indication for shoulder OA. Iovera also had a strong start to 2026, with first quarter sales increasing 21% over 2025. We’re starting to see the benefits from last year’s rollout of a product-specific reimbursement code and a dedicated sales force staffed with experienced medical device account managers.

From a lifecycle management perspective, our registrational study in spasticity is on track with top-line results expected by year-end. Here, the unmet need remains high, with 6.3 million patients with spasticity seeking treatment each year in the U.S. Together, we believe our strong commercial performance in advancing lifecycle management will support durable top-line growth. Importantly, this momentum further strengthens our leadership in post-surgical pain control and early intervention OA pain management. In tandem with the momentum across our commercial portfolio, through our 5x30 strategy, we are now advancing an innovative clinical-stage pipeline. Here, we’re prioritizing mechanistically de-risked assets with the potential to drive shareholder value well beyond 2030. In addition to clinical data readouts for our commercial products, our clinical-stage assets are entering a catalyst-rich period.

Key upcoming milestones include PCRX-201, our locally administered gene therapy for knee OA, remains on track for top-line data later this year. With approximately 15 million people in the U.S. affected by knee OA and limited durable treatment options, the unmet need remains high. I’ll talk in greater detail about PCRX-201 shortly. PCRX-2002, our novel hydrogel formulation of the non-opioid analgesic ropivacaine for post-surgical pain. PCRX-2002 was designed to deliver rapid onset and long-acting analgesia from a single application at the time of surgery. We expect to begin phase II development later this year. This asset has the potential to complement EXPAREL as an easy-to-use, longer-acting therapy with patent protection extending to 2042. Additionally, our gene therapy platform continues to generate promising preclinical candidates to advance our 5x30 pipeline goal.

These include PCRX-1003 for degenerative disc disease, PCRX-1002 for dry eye disease, PCRX-1001 for canine OA, which we believe has significant out-licensing potential. Let me briefly highlight PCRX-201, our lead HCAd program, which represents a potential paradigm shift for the treatment of knee OA. Building on the encouraging durability we observed in our phase I study, our two-part phase II ASCEND study is on track. Part A is fully enrolled with 49 patients, as previously mentioned, we’ll have top-line results from this 52-week study later this year. Like most phase II studies, ASCEND is not powered for efficacy. The primary objective is safety. We’ll also be looking for efficacy trends. Key secondary endpoints include changes in pain and function from baseline as measured by numerical rating scale, WOMAC, and KOOS scores. In parallel, we’re advancing a commercially viable manufacturing process for PCRX-201.

This work is critical to enabling the initiation of Part B around mid-year. We expect Part B to enroll roughly 90 additional patients across 3 arms, two different doses of PCRX-201, and an active steroid comparator. While it’s premature to quantify the commercial opportunity, we believe PCRX-201 has 3 key attributes that underscore its market potential. First is durability. We believe that demonstrating a treatment effect lasting 1 year will represent a transformational advance in knee OA. This would be significantly longer than currently available knee OA treatments, which generally provide durability of approximately 3-6 months. Second is cost of goods. PCRX-201 is locally delivered. This differs from systemic approaches requiring much higher dosing to achieve the desired effect. Lower dose levels coupled with efficient manufacturing support a favorable and commercially viable cost of goods profile.

This is an important consideration for any therapy intended for chronic high-prevalence conditions like osteoarthritis. Third is health economic value. If the durability we’re targeting is borne out clinically, we believe PCRX-201 could offer attractive value for the healthcare system. As a reminder, PCRX-201 is an IL-1 receptor antagonist. IL-1 is a well-validated de-risked target for reducing inflammation. There are currently two FDA-approved drugs that block the IL-1 pathway in other inflammatory joint conditions. Neither one is practical for early OA intervention because their short half-life would require very high systemic doses or daily knee injections. PCRX-201 is complementary to Zilretta and iovera and could expand our leadership in early intervention OA pain management. Briefly turning to partnerships, which remain a key pillar of our 5x30 strategy. We’re taking a disciplined, targeted approach to business development.

We’re prioritizing strategically aligned assets that are financially accretive and leverage our commercial infrastructure. In parallel, we’re utilizing strategic partnerships to access new sources of revenue by expanding our commercial reach into untapped U.S. and international markets. Our strategic collaboration with market leaders Johnson & Johnson MedTech and LG Chem are both excellent examples of our strategy in motion. These partnerships advance our goal of 5 partnerships by 2030 and efficiently expand our commercial coverage and geographic reach. In summary, we’re pleased with our first quarter results and the momentum behind our 5x30 strategy. With clear progress across every 5x30 goal, we remain confident we’ll deliver sustainable growth and value creation into and well beyond 2030. With that, I’d like to turn the call over to Brendan Teehan to share more details on our first quarter commercial performance. Brendan Teehan?

Brendan Teehan, Chief Commercial Officer, Pacira BioSciences, Inc.: Thank you, Frank, and good afternoon to all joining us today. I’m pleased to report that the upward momentum we observed in the second half of 2025 has continued into 2026. Our commercial execution is on point. Demand trends are strong across the complete portfolio, we’re delivering top-line growth consistent with what we previewed in February. I’ll start with our flagship product, EXPAREL, where we’re outperforming last year’s first quarter volume growth while continuing to expand patient and provider access. We continue to see excellent momentum in hospital outpatient and ASC settings, where an increasing number of EXPAREL-assisted procedures are taking place and where our customers are seeing favorable reimbursement. Our focus beyond sharing excellent clinical outcomes is demonstrating the enhanced economic value of EXPAREL.

To support this, we recently presented data from real-world studies highlighting EXPAREL’s compelling value proposition, along with several health economics and outcome studies at key congresses that include the Orthopaedic Research Society, the American Academy of Orthopaedic Surgeons, and the Academy of Managed Care Pharmacy. These real-world data demonstrate both the clinical and economic value EXPAREL delivers. We look forward to reporting additional data readouts as the year progresses. Our initiatives include the comprehensive real-world IGOR registry, which now has more than 3,500 OA patients enrolled and is providing valuable information for EXPAREL, Zilretta, iovera, as well as other treatments. These data are helping guide best practice for knee OA patients across their treatment journey. Importantly, commercial payers continue to recognize the EXPAREL value proposition and implement NOPAIN-like policies that reimburse outside the surgical bundle.

We have now surpassed 110 million covered lives with separate reimbursement outside of the bundle for EXPAREL. With a growing critical mass of coverage, we expect accelerating change in the market throughout the remainder of the year. In short, we are extremely encouraged by the progress made in the first quarter, building on the momentum from 2025. Demand is being driven by powerful combination of expanding reimbursement, growing protocol adoption, and compelling real-world evidence, all supporting each other and growing our business. With a strong finish to 2025 and a solid start to 2026, EXPAREL continues to gain share as institutions commit to best practice opioid-sparing care. We remain confident in our ability to deliver durable, sustainable growth for EXPAREL as access widens and best practices evolve.

Turning to Zilretta and iovera, both products are off to a strong start to 2026 as valuable commercial investments we made last year begin to bear fruit. As you know, last year, we rolled out a dedicated Pacira sales force for Zilretta to ensure a focused promotional impact. In addition, we essentially tripled our U.S. commercial reach for Zilretta through a strategic collaboration with J&J MedTech. For iovera, we are benefiting similarly from a dedicated sales force we onboarded last year. Looking ahead, we believe both Zilretta and iovera have significant upside potential to become more meaningful sources of revenue. In summary, we’re pleased with the strong start to 2026 across our three commercial products. We believe we are well-positioned to deliver a successful year of sustainable top-line growth. With that, I will turn the call over to Shawn for his financial review.

Shawn Cross, Chief Financial Officer, Pacira BioSciences, Inc.: Thank you, Brendan. I’ll start with an update on sales and margin trends. First quarter EXPAREL net sales increased to $143.3 million, versus $136.5 million in 2025. Volume growth of approximately 7% was partially offset by a shift in vial mix and discounting from our third GPO going live last year. First quarter sales were also impacted by winter storms disrupting shipping and triggering returns. As we move forward in 2026, we expect the delta between volume and revenue growth for the second quarter to be similar to the second half of 2025 and then narrow as we anniversary our third GPO agreement mid-year. For ZILRETTA, first quarter sales improved by 15% to $26.8 million, versus the $23.3 million we reported in 2025.

As Brendan Teehan mentioned, this was largely attributable to the growth initiatives implemented last year, including our dedicated Zilretta sales force. For iovera, sales increased 21% to $6.2 million, compared to $5.1 million in the first quarter of 2025. Again, as Brendan Teehan mentioned earlier, this was largely attributable to the growth initiatives implemented last year, including our dedicated iovera sales force. Turning to gross margins. On a consolidated basis, our first quarter non-GAAP gross margin was 80%, versus 81% for last year. Gross margins continue to benefit from the improved cost and efficiencies of our enhanced larger scale EXPAREL manufacturing process and continuous improvement initiatives at both of our manufacturing facilities. The non-GAAP R&D expense, the first quarter increased to $25.4 million from $23.1 million reported last year.

This increase relates to our advancing phase II study of PCRX-201 as well as our label expansion studies, all of which have anticipated top line readouts later this year. In addition, we’re supporting 3 promising HCAd-based preclinical programs. Non-GAAP SG&A expense came in at $83.9 million for the first quarter versus $76.2 million last year. You may recall that last year’s SG&A expense was positively impacted by a favorable outcome to litigation and subsequent recovery of $5.2 million in legal fees. Taking this into account, we are largely in line with last year. As we discussed last quarter, we’re now leveraging our existing commercial infrastructure, which is well equipped to support top line growth. All of this resulted in another quarter of significant adjusted EBITDA of approximately $40.2 million for the first quarter.

As for the balance sheet, we continue to be in a position of strength and ended the quarter with $202 million in cash and investments. With a strong balance sheet and a business that is producing significant operating cash flow, we believe we are well equipped to advance our 5x30 growth strategy and create shareholder value. With respect to capital deployment, we will continue to maintain a disciplined and strategic approach, focusing on three key areas. First, driving top line growth by leveraging our existing commercial infrastructure. Second, advancing an innovative pipeline and becoming the leader in musculoskeletal pain and adjacencies. We are prioritizing accretive end market assets to leverage our established commercial footprint and de-risk clinical stage programs. Third, opportunistically returning capital to shareholders. During the first quarter, we executed another $50 million in share repurchases.

As a result, we retired approximately 2.2 million shares of common stock. Since last year’s start of the plan, we have decreased our share count by a total of approximately 9 million shares and reduced our outstanding common shares to 39.3 million. To remind you, as of March 31st, we had $100 million remaining under our share buyback authorization, which runs through the end of this year. Going forward, we remain committed to maintaining favorable operating margins while advancing our 5x30 strategy. This brings us to our full year financial guidance for 2026, which we are reiterating today as follows. Total revenues of $745 million-$770 million. For EXPAREL, net product sales of $600 million-$620 million.

With respect to quarterly trends, we anticipate the remainder of 2026 will largely follow historical patterns. For Zilretta and iovera, our guidance assumes 2026 will be largely in line with 2025. While we are encouraged by both products’ start to the year, we will wait to gain more visibility before updating our assumptions. The final component of our 2026 revenue guidance relates to $7 million in expected revenue from our licensing agreement for the veterinary market. Non-GAAP gross margins of 77%-79%. With respect to quarterly cadence, we expect the next two quarters to continue to benefit from the sale of lower cost EXPAREL inventory. For the fourth quarter, we expect margins to be slightly below our full year guidance range due to the sale of higher cost inventory as well as shutdown-related costs and other expenses.

Non-GAAP R&D expense of $105 million-$115 million. As we prepare to initiate part B of our phase II ASCEND study of PCRX-201 and certain EXPAREL and Zilretta product development efforts, we expect an uptick in R&D expense during the second quarter, followed by a slight decline in quarterly spend as compared to the second quarter in the back half of the year. Non-GAAP SG&A expense of $320 million-$340 million. With respect to the timing of SG&A spending, we expect the first half of the year to be higher than the second half as a result of proxy-related activities. Stock-based compensation of $54 million-$62 million. Lastly, for those modeling adjusted EBITDA, we expect our 2026 depreciation expense to be approximately $30 million. With that, I’ll turn the call back over to Frank.

Frank Lee, Chief Executive Officer, Pacira BioSciences, Inc.: Thank you, Shawn. In closing, 2026 is off to a strong start. Pacira is operating with momentum, clarity and discipline. Our 5x30 strategy is driving strong execution and reinforcing our leadership in post-surgical pain and early intervention OA pain management. We look forward to building on this momentum and positioning the company for sustainable growth and value creation through and beyond 2030. Thank you again for joining us today and for your continued support and confidence in our mission. With that, we’re ready to open up the call for questions. Operator?

Conference Call Operator: Our first question will come from the line of Douglas Miehm of H.C. Wainwright & Co. Your line is open, Douglas.

Douglas Miehm, Analyst, H.C. Wainwright & Co.: Hi. Good afternoon. Thanks for taking the questions. A few questions. Maybe Shawn, just as a starting point, if you could help us walk through a little bit about the cadence for R&D spend through the rest of the year. Just to confirm, it sounds like we’re gonna have a step-up in 2Q, followed by then sort of a re-step down in the third quarter, you know, just as we see PCRX-201 ramp up. You know, just sort of should we think then more spend in 2027? Thank you. I have a follow-up.

Frank Lee, Chief Executive Officer, Pacira BioSciences, Inc.: Hey, hey Doug, Frank here. Thanks for the question. Let me just turn it over to Shawn, and he can walk us through that a little bit here.

Shawn Cross, Chief Financial Officer, Pacira BioSciences, Inc.: Thanks, Frank, and thanks for the question, Doug. As mentioned in my remarks a few minutes ago, we were preparing for initiation of Part B of the ASCEND study for PCRX-201, which we’re excited about, and then certain EXPAREL product development efforts. We do expect an uptick in Q2 from the $25.4 million in Q1 that we spent. Just to provide a little more detail, we expect it to be in the low $30 million range, and then we’ll come back down closer to the Q1 levels in Q3 and Q4. That’s how we see it playing out. We’ll obviously provide more updates as we get through the year.

Douglas Miehm, Analyst, H.C. Wainwright & Co.: Okay, great. That’s very helpful, with that specificity. Then just at a, at a macro level, you know, 1 thing that I’ve been curious about is sort of the expiration of the Obamacare subsidies. We’ve started to see some decline in terms of enrollments. You know, I think if we look at results for some of the med tech companies in the 1st quarter and even some of the hospital names that have not seen anything dramatic. I’m just curious, you know, what you are hearing, you know, from sort of the hospital channel, you know, in terms of their perspective on what how they’re thinking about the rest of the year playing out. Thank you.

Frank Lee, Chief Executive Officer, Pacira BioSciences, Inc.: Thanks, Doug. listen, we stay close to this, so let me turn this one over to Brad to give his perspective.

Brendan Teehan, Chief Commercial Officer, Pacira BioSciences, Inc.: Doug, thanks so much for the question. Obviously, we’re always looking at the broader macro environment. I’m sure that people are taking a look at what those changes will mean to them individually. We will keep a close eye on those procedures where EXPAREL is, you know, favored for addressing, and we’ll continue to kind of give updates as we see it play out. I think it’s just too early to say.

Douglas Miehm, Analyst, H.C. Wainwright & Co.: Okay, great. Thank you very much, and I’ll jump out for now.

Conference Call Operator: Our next question will be coming from the line of Dennis Ding of Jefferies. Your line is open, Dennis.

Anthea, Analyst, Jefferies: Hi, this is Anthea on for Dennis. Thanks for taking our question. Earlier this week, we saw data from a cell-free regenerative therapy for knee OA, with a headline efficacy of 93% of patients demonstrating clinically meaningful improvements in mobility and pain reduction. There’s not a lot of information on that trial, so I’m curious how you guys are framing that data and how PCRX-201 will differentiate from that product. Any additional color on what promising efficacy trends would look like for PCRX-201’s readout would be helpful as well. Thank you.

Frank Lee, Chief Executive Officer, Pacira BioSciences, Inc.: Hey, thanks for the question. I didn’t get the name of the company you mentioned. What was that?

Anthea, Analyst, Jefferies: I think Creative Medical Technology.

Frank Lee, Chief Executive Officer, Pacira BioSciences, Inc.: Okay. There are a lot of different cell and regenerative therapy companies out there. Let me turn it over to Jonathan to see if he has any perspective on that because of course, there are lots of different studies out there with various levels of rigor.

Jonathan Slonin, Chief Medical Officer, Pacira BioSciences, Inc.: Thanks, Frank. Not commenting on any specific company. We are confident that the HCAd platform is the right modality for sustained relief of knee osteoarthritis. We have made tremendous progress in scaling up. We are finalizing our commercial scale manufacturing for Part B. As we’ve articulated before, anticipated enrollment is right on time. To answer your second question, we’re expecting the top-line data from Part A to read out at the end of the year. Just to remind you, its primary efficacy is safety. What we will be looking at is the totality of the data to understand how PCRX-201 performs in a randomized clinical control trial with an active comparator.

We are looking at safety as our primary efficacy, but we will also be looking at the secondary endpoints around efficacy as well. We will be reviewing that data, and then we’re gonna go forward, we’ll assess where we are at. The trends that we’re looking for are trends consistent with durability and efficacy from our phase I trial.

Anthea, Analyst, Jefferies: Okay. Thank you.

Conference Call Operator: Our next question will be coming from Leszek Sulewski of Truist Securities. Your line is open, Les.

Brendan Teehan, Chief Commercial Officer, Pacira BioSciences, Inc.0: Hey, this is Jeevan on for Les. Thanks for taking our questions.

How would you characterize elective procedure trends exiting March? Any lasting impact from the winter storms? Separately, how should we think about potential upside from ex-US partnerships across the portfolio? Thank you.

Frank Lee, Chief Executive Officer, Pacira BioSciences, Inc.: Hey, thanks for the question, Jeevan. I’ll ask Brendan Teehan to comment a little bit about what we saw and what we’re seeing now. He mentioned it a little bit earlier. I’ll let him comment on that a little bit. I’ll mention a little bit about what to expect on ex-US partnerships. Brendan Teehan.

Brendan Teehan, Chief Commercial Officer, Pacira BioSciences, Inc.: Yeah. Les, thank you so much for the question. If we look at the moving annual total for procedures where EXPAREL would assist, that’s largely flat year-over-year, despite EXPAREL being up over 7%. If we look specifically at the first quarter, market procedures are up in the mid-single digits. I would say 4%-5%, as opposed to EXPAREL. If that gives you some sense. Then we’ll look to see how that progresses here in the second quarter.

Frank Lee, Chief Executive Officer, Pacira BioSciences, Inc.: Just to answer your question about ex-U.S. partnerships. Let me take a step back here a little bit. This is an important part of our 5x30 strategy in terms of signing 5 partnerships, both here in the U.S. and ex-U.S. As you know, ex-U.S., we’ve signed a partnership with LG Chem, they’re a leading company in Asia Pacific. We have plans to sign similar types of partnerships in the other major geographies. It’s premature to provide guidance on these kinds of partnerships and top-line impact, but I would say it’s not insignificant. These will be important partnerships that’ll drive revenue not only through 2030, but well beyond 2030. That’s where we stand now.

As you know, the first partnership, the intention is to file, in the not too distant future. So we’ll be updating you on guidance around that, starting in 2027.

Conference Call Operator: Our next question will be coming from the line of Serge Belanger of Needham & Company. Your line is open.

Serge Belanger, Analyst, Needham & Company: Hi, good afternoon. Thanks for taking our questions. The first one, kind of a follow-up to the previous question around the impact of winter storms. I think you were expecting a potential softer 1Q because of those storms. Looks like all 3 of your products had some pretty solid year-over-year growth. Just curious if there was any impact or you were able to recapture it over the remainder of the quarter. My second question regarding NOPAIN Act. If I remember correctly, the NOPAIN Act has kind of a 3-year term ending in 2027. Just curious if there’s any legislation in development here to extend or modify that term. Thanks.

Frank Lee, Chief Executive Officer, Pacira BioSciences, Inc.: Yeah, thanks for your question, Serge. Regarding the winter storm, we can provide a little bit more color on this, so I’ll turn to Brendan Teehan for that. Brendan Teehan, maybe you can talk a little bit about what we saw in the winter storms. I’ll speak to NOPAIN Act.

Brendan Teehan, Chief Commercial Officer, Pacira BioSciences, Inc.: Yeah, sure. Thank you so much for the question, Serge. The winter storms do have an impact. They impact both the ability to ship, but also, as you would expect in those geographies, where those surgeries might have taken place, those surgeries did not happen, which lead to rescheduling, not necessarily within the quarter. I think there is some kind of carryover as patients look to be rescheduled for those procedures. Despite that, I think we are very pleased with the performance of EXPAREL volume, vis-a-vis the total available market. That’s what I would say for winter storms. I believe we are past that and, you know, looking forward to the second quarter.

Frank Lee, Chief Executive Officer, Pacira BioSciences, Inc.: Thanks, Brent. Serge, with regard to your question about NOPAIN, thanks for that. NOPAIN indeed, initially is scheduled to expire at the end of 2027. That said, we have been staying very close to CMS and other stakeholders. What we’re very encouraged about is not only the uptake of NOPAIN, but also the expansion of coverage to commercial lives. Brent mentioned earlier that now we have a total of $110 million outside the bundle and growing. As you know, NOPAIN is primarily covering Medicare lives. What we can tell you is that we’re very encouraged by the discussions we’ve had about the market research and the uptake of NOPAIN with CMS and other stakeholders. We’re gonna confirm a lot of what we’re seeing through claims analysis.

I would say that NOPAIN is doing what it’s intended to do, and the commercial payers are also coming on board, which is highly encouraging.

Serge Belanger, Analyst, Needham & Company: Thank you.

Conference Call Operator: Our next question will be coming from the line of Hardik Parikh of JPMorgan. Your line is open.

Hardik Parikh, Analyst, JPMorgan: Hey, everybody. Thanks for taking my question. I just wanted to ask you about Shawn, I think I heard you say you expect SG&A to be lower in the second half. Can you talk to the magnitude of the step down you’re expecting in the second half? Then, just SG&A seems to have elevated the past 5 quarters of relative to 2024. I’m just trying to get a sense of what the normalized run rate is going forward. Thank you.

Frank Lee, Chief Executive Officer, Pacira BioSciences, Inc.: Hey, thanks for that, Hardik. Let me turn it to Shawn here.

Shawn Cross, Chief Financial Officer, Pacira BioSciences, Inc.: Thanks for the question. If you look at, we reported $83.9 million in SG&A this quarter. You can take a look at, without providing, you know, super specific detail, but you can take a look at the information we filed in our proxy on, it was Tuesday or Wednesday. I’m losing track of time here. That provides some of the magnitude of what we anticipate spending during proxy season. That would be, you know, above and, you know, the typical sort of course of events. We anticipate sort of coming back down in Q3 and Q4 to sort of, you know, perhaps a little bit below where we, where we even spent in this quarter, kind of generally directionally correct.

Hardik Parikh, Analyst, JPMorgan: Thank you.

Conference Call Operator: I would now like to turn the conference back to Susan for closing remarks.

Susan Mesco, Head of Investor Relations, Pacira BioSciences, Inc.: Thank you, operator, and thanks to all on the call for your questions and time today. We’re excited about the opportunities ahead and remain focused on executing our 5x30 growth strategy with discipline and purpose. As we look to the remainder of 2026, we are confident in our ability to build on our momentum and position Pacira for long-term success. Thank you again for your continued support. Good night.

Conference Call Operator: This concludes today’s program. Thank you for participating. You may now disconnect.