Analyst Ratings January 26, 2026

H.C. Wainwright Lifts ImmunityBio Price Target to $10 After ANKTIVA Regulatory Progress

Analyst upgrades, positive FDA guidance and multiple clinical signals bolster outlook for IBRX amid ongoing financings

By Caleb Monroe IBRX
H.C. Wainwright Lifts ImmunityBio Price Target to $10 After ANKTIVA Regulatory Progress
IBRX

H.C. Wainwright increased its price target for ImmunityBio Inc. (IBRX) to $10.00 from $8.00 and kept a Buy rating following favorable regulatory feedback for the company’s ANKTIVA therapy and encouraging clinical results across multiple programs. Other firms have also raised targets, and recent corporate financing flexibility adds to investor attention. The FDA has outlined a path for potential sBLA resubmission in BCG-Unresponsive papillary bladder cancer without requesting new clinical trials, and ImmunityBio reported longer-term survival and cystectomy-avoidance data that underpinned the agency’s guidance.

Key Points

  • H.C. Wainwright raised its price target on ImmunityBio to $10.00 from $8.00 and kept a Buy rating; the new target represents about 55% upside from the cited $6.45 stock price.
  • The FDA outlined a potential resubmission path for ANKTIVA in BCG-Unresponsive papillary bladder cancer allowing additional information to be filed within 30 days without the need for new clinical trials; five-year follow-up data showing 96% bladder cancer-specific survival at 36 months and strong cystectomy-avoidance rates were key.
  • Corporate and market developments include an amended $505 million convertible promissory note permitting partial conversions, other firms raising price targets, and InvestingPro data showing a low negative beta for IBRX - factors that may influence investor positioning in biotech and healthcare sectors.

Analyst update and market context

H.C. Wainwright raised its price objective on ImmunityBio Inc. (NASDAQ: IBRX) to $10.00 from $8.00 and maintained a Buy rating, citing recent developments for the company’s lead immunotherapy, ANKTIVA. The new target equates to a roughly 55% upside from the stock’s cited price of $6.45.

According to InvestingPro data referenced in the reporting, the analyst consensus remains strongly bullish with an aggregated recommendation rating of 1.2 and a range of individual price targets spanning $7 to $24.


Regulatory feedback on ANKTIVA in bladder cancer

The Food and Drug Administration provided guidance that opens a potential resubmission route for ANKTIVA in BCG-Unresponsive papillary bladder cancer. The agency has allowed ImmunityBio to submit additional information within 30 days to support an sBLA resubmission and did not require new clinical trials as part of that path.

Central to the FDA’s stance were follow-up outcomes extending to five years. The dataset showed a bladder cancer-specific survival rate of 96% at 36 months, and the median survival time had not been reached at the five-year mark. Reported cystectomy-avoidance rates were 92% at one year and 82% at three years.


Clinical results in other indications

ImmunityBio also disclosed that median overall survival remains unreached for patients with recurrent glioblastoma treated with a chemo-free combination of ANKTIVA plus CAR-NK therapy; 19 of 23 patients enrolled in that trial were still alive as of January 22, 2026.

Separately, trial data from the QUILT-106 study were reported showing sustained complete responses in patients with Waldenstrom’s lymphoma treated with CAR-NK cell therapy. Two patients remain in complete remission at 7 and 15 months respectively, with no chemotherapy or additional therapy reported.


Financial position and corporate developments

Although ImmunityBio was not profitable over the last twelve months, its balance sheet displays liquid assets that exceed short-term obligations, reflected in a current ratio of 5.77. The company is described as operating with a moderate level of debt.

On the financing front, ImmunityBio amended a $505 million convertible promissory note with Nant Capital, LLC, to permit partial conversions of outstanding principal into common stock prior to the note’s maturity. The noteholder is an entity affiliated with Dr. Patrick Soon-Shiong.


Other analyst moves

Following the regulatory and clinical updates, other investment firms adjusted their valuations. BTIG lifted its price target to $9 from $6 and kept a Buy rating, noting an improved outlook after material developments. Piper Sandler bumped its target to $7 from $5, pointing to robust ANKTIVA sales and a recent accelerated approval by the Saudi Food and Drug Authority for certain cancer indications.


Market behavior and additional insights

InvestingPro data cited in the reporting indicates ImmunityBio’s stock exhibits a beta of -0.04, suggesting the security has tended to move inversely to the broader market, a characteristic some investors view as potential portfolio diversification. The data source also notes that subscribers have access to more than a dozen additional ProTips on IBRX’s financial health and valuation.


Company response timeline and next steps

ImmunityBio has described its discussions with the FDA regarding ANKTIVA as productive. The agency recommended the submission of extra information for a potential resubmission, did not request new clinical trials, and the company intends to respond within the 30-day window communicated by regulators.

Taken together, the regulatory guidance, long-term follow-up survival results, ongoing glioblastoma and lymphoma program updates, adjustments to the convertible note, and fresh analyst price targets illustrate concurrent clinical and financial developments shaping the market’s view of ImmunityBio.

Risks

  • Regulatory uncertainty remains until the company submits the additional information and the FDA completes its review - this impacts the biotech and healthcare sectors.
  • ImmunityBio has not been profitable over the last twelve months despite liquid assets exceeding short-term obligations; ongoing cash management and financing terms could affect operational flexibility in the near term.
  • Clinical programs, while showing encouraging signals, still carry typical development and commercialization risks; outcomes in glioblastoma and lymphoma trials will affect company valuation and investor sentiment in oncology equities.

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