Analyst Ratings January 29, 2026

H.C. Wainwright Boosts Nurix Price Target to $32 After Q4 Fiscal 2025 Results

Analyst maintains Buy rating as Nurix reports narrower-than-expected loss, solid cash reserves and ongoing pipeline milestones for Bexdeg

By Maya Rios NRIX
H.C. Wainwright Boosts Nurix Price Target to $32 After Q4 Fiscal 2025 Results
NRIX

H.C. Wainwright raised its price target on Nurix (NRIX) to $32.00 from $31.00 while keeping a Buy rating after the company's fourth-quarter fiscal 2025 results. The updated target implies about 79% upside from the current share price of $17.87 and sits above the analyst consensus average of $27.70. Nurix reported a net loss of $0.82 per share for the quarter, collaboration revenue of $13.6 million and ended the period with $592.9 million in cash and equivalents, which H.C. Wainwright says should fund operations into the second half of 2027.

Key Points

  • H.C. Wainwright raised its price target on Nurix to $32.00 from $31.00 and kept a Buy rating, implying roughly 79% upside from the current $17.87 share price.
  • Nurix reported a Q4 fiscal 2025 net loss of $0.82 per share, slightly better than H.C. Wainwright’s $0.84 estimate; trailing-twelve-month diluted EPS was -$2.97 per InvestingPro data.
  • Quarterly collaboration and license revenue totaled $13.6 million (below the $15.0 million estimate), R&D expenses were $83.0 million (below the $87.8 million estimate), and SG&A expenses matched projections at $13.6 million; the company held $592.9 million in cash, which H.C. Wainwright expects to fund operations into H2 2027.

H.C. Wainwright raised its price objective on Nurix Therapeutics to $32.00 from $31.00 on Thursday and kept a Buy rating following the company’s fourth-quarter fiscal 2025 financial report. The firm’s revised target implies roughly 79% upside relative to Nurix’s prevailing share price of $17.87, and it is modestly above the broader analyst consensus average target of $27.70.

Nurix’s quarterly results showed a net loss of $0.82 per share, a slight improvement compared with H.C. Wainwright’s own estimate of a $0.84-per-share loss. The company remains unprofitable on a trailing-twelve-month basis, with InvestingPro data indicating a diluted EPS of -$2.97 over the last 12 months.

Revenue from collaboration and license arrangements for the quarter came in at $13.6 million, below H.C. Wainwright’s $15.0 million estimate. Research and development expenses were reported at $83.0 million for the quarter, beneath the research firm’s expectation of $87.8 million. Selling, general and administrative costs matched the firm’s projection at $13.6 million.

Nurix finished the quarter with about $592.9 million in cash and cash equivalents. H.C. Wainwright interprets that cash balance as sufficient to fund the company's operations into the second half of 2027. Supporting metrics from InvestingPro show a current ratio of 5.35 and indicate that Nurix’s liquid assets exceed its short-term obligations. The company’s market capitalization stood at $1.81 billion at the time of the report.

Several other research firms updated their views on Nurix in recent days. Morgan Stanley upgraded Nurix from Equalweight to Overweight and raised its price target sharply to $36.00 from $15.00, citing increased confidence in the company’s lead candidate, Bexdeg, as it moves toward pivotal development. RBC Capital raised its price target to $30.00 from $28.00 and maintained an Outperform rating, while describing the reported quarter as "uneventful." BTIG reiterated a Buy rating with a $30.00 price target, noting Nurix’s cash position and progress across key programs.

Nurix has outlined objectives for 2026 centered on advancing its BTK degrader, Bexdeg. The company plans to move Bexdeg into pivotal development for relapsed/refractory chronic lymphocytic leukemia, including execution of a Phase 2 study and initiation of a confirmatory Phase 3 trial aimed at supporting global registration. Additionally, Nurix intends to broaden Bexdeg’s development into autoimmune and inflammatory indications with a new tablet formulation and targets an IND submission for that formulation in 2026.

InvestingPro data cited in the company’s reporting indicates that Nurix is trading close to its Fair Value. The mix of an improving but still negative EPS trend, a cash runway that extends into mid-2027 by H.C. Wainwright’s measure, and the active clinical development plan for Bexdeg frame the company’s current position: a biotech with ongoing development milestones and a significant cash cushion despite not yet reaching profitability.


Contextual note: The figures and analyst ratings above reflect the company’s disclosed fourth-quarter fiscal 2025 results and subsequent analyst reactions. The information presented here follows the reported data and the stated viewpoints of the named research firms.

Risks

  • Continued unprofitability: Nurix reported a quarterly net loss and a negative diluted EPS of -$2.97 over the last 12 months, highlighting ongoing profitability challenges relevant to the biotechnology and healthcare sectors.
  • Revenue shortfall versus estimates: Collaboration and license revenue of $13.6 million came in below the $15.0 million estimate, a near-term market and commercial risk affecting investor expectations and capital markets sentiment toward biotech firms.
  • Reliance on cash reserves for operations: While Nurix held $592.9 million in cash and equivalents and a current ratio of 5.35, H.C. Wainwright’s assessment that this should fund operations only into the second half of 2027 underscores liquidity and funding-timeline risks for the company and the pharmaceutical financing landscape.

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