Analyst Ratings February 4, 2026

Cantor Fitzgerald Lifts Amgen Target to $350 After Strong Q4 Results, Keeps Neutral Rating

Analyst raises price objective citing pipeline revisions and near-term EPS upside amid mixed quality of recent sales gains

By Priya Menon AMGN
Cantor Fitzgerald Lifts Amgen Target to $350 After Strong Q4 Results, Keeps Neutral Rating
AMGN

Cantor Fitzgerald increased its price target for Amgen to $350 from $315 while retaining a Neutral rating after the company reported fourth-quarter revenue and earnings that beat consensus. The firm cited higher near-term EPS estimates, pipeline changes and moderated R&D spending as drivers of the target increase, even as some recent upside reflected lower-quality tailwinds such as Prolia sales and inventory builds.

Key Points

  • Cantor Fitzgerald raised its Amgen price target to $350 from $315 and kept a Neutral rating after the company’s Q4 beat on revenue and EPS.
  • Amgen reported Q4 revenue of $9.87 billion and EPS of $5.29, both above consensus; strong sales were led by Prolia, Repatha, Evenity and Uplizna.
  • Other firms also moved targets higher: RBC Capital to $360 (Outperform) and TD Cowen to $420 (Buy); Amgen provided 2026 guidance implying 1-4% revenue growth and EPS of $21.60-23.00.

Cantor Fitzgerald raised its price target on Amgen (NASDAQ:AMGN) to $350.00 from $315.00 on Wednesday, while leaving the stock’s analyst recommendation at Neutral.

The firm said the move followed Amgen’s fourth-quarter performance, which exceeded expectations on both the top and bottom lines. Revenue for the period came in at $9.87 billion, topping the consensus figure of $9.47 billion. Reported earnings per share were $5.29, beating the expected $4.73 by $0.56. Separately, Cantor Fitzgerald noted the company’s top-line outperformance versus consensus by $396 million and an EPS beat of $0.60 versus expectations.

Cantor Fitzgerald’s note highlighted that portions of the upside reflected lower-quality tailwinds, specifically stronger-than-expected Prolia sales and inventory builds. Despite that caveat, the analyst team pointed to sufficient strength across other franchise drivers - including Repatha and Uplizna - to justify a likely upward revision to fiscal 2026 estimates.

Management’s guidance range further informed the analyst view. Amgen forecast topline growth of 1-4%, compared with street expectations centered on 1%. The company also provided EPS guidance of $21.60 to $23.00, which Cantor Fitzgerald described as straddling the psychologically important $22 per share mark and implying a trajectory toward the mid-$22 range.

The research house said its decision to raise the price target reflected a combination of pipeline revisions, higher near-term EPS projections and moderated research and development spending.

Other sell-side responses to the quarter were similarly constructive on valuation. RBC Capital raised its Amgen price target to $360 from $335 and maintained an Outperform rating. TD Cowen increased its target to $420 from $389 and kept a Buy rating, citing Amgen’s fiscal 2026 guidance as addressing concerns about upcoming loss of exclusivity for key products.

Amgen’s quarterly results were driven by solid sales across key products, notably Prolia, Repatha, Evenity and Uplizna. Company executives also highlighted promising pipeline developments during the earnings call. Despite the favorable results and analyst target increases, Amgen’s shares fell modestly in aftermarket trading.


Notable figures from the quarter:

  • Revenue: $9.87 billion (consensus $9.47 billion)
  • EPS: $5.29 (consensus $4.73)
  • Cantor Fitzgerald price target: raised to $350 from $315; rating Neutral
  • RBC Capital price target: $360 from $335; rating Outperform
  • TD Cowen price target: $420 from $389; rating Buy

The balance of stronger operational drivers and some transient tailwinds has shaped analyst expectations for fiscal 2026 and informed divergent firm-level price targets and recommendations.

Risks

  • Some of the recent upside was attributed to lower-quality tailwinds such as elevated Prolia sales and inventory builds, which could make future comparisons more difficult - impacts the healthcare and pharmaceutical sectors.
  • Loss of exclusivity for key products remains a concern referenced by analysts, affecting revenue predictability in the biotech and broader healthcare markets.
  • Guidance uncertainty around fiscal 2026 and the range of EPS could create volatility in Amgen’s stock performance despite near-term beats - relevant to equity markets and investor sentiment.

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